Evaluating testosterone as a phenotypic integrator: from tissues to individuals to species

SE Lipshutz, EM George, AB Bentz… - Molecular and cellular …, 2019 - Elsevier
Highlights•Testosterone (T) is thought to integrate phenotypes that work well
together.•However, it is not clear how such integration is generated within the organism.•T …

How research on female vertebrates contributes to an expanded challenge hypothesis

KA Rosvall, AB Bentz, EM George - Hormones and Behavior, 2020 - Elsevier
The bi-directional links between hormones and behavior have been a rich area of research
for decades. Theory on the evolution of testosterone (T) was greatly advanced by the …

Multivariate models of animal sex: breaking binaries leads to a better understanding of ecology and evolution

JF McLaughlin, KM Brock, I Gates… - Integrative and …, 2023 - academic.oup.com
Synopsis “Sex” is often used to describe a suite of phenotypic and genotypic traits of an
organism related to reproduction. However, these traits—gamete type, chromosomal …

A single gene orchestrates androgen variation underlying male mating morphs in ruffs

JL Loveland, A Zemella, VM Jovanović, G Möller… - Science, 2025 - science.org
Androgens are pleiotropic and play pivotal roles in the formation and variation of sexual
phenotypes. We show that differences in circulating androgens between the three male …

Neuroinflammation

D Mukhara, U Oh, GN Neigh - Handbook of Clinical Neurology, 2020 - Elsevier
Neuroinflammation is implicated in contributing to a variety of neurologic and somatic
illnesses including Alzheimer's disease (AD), Parkinson's disease (PD), and depression. In …

Female ornamentation is associated with elevated aggression and testosterone in a tropical songbird

ED Enbody, J Boersma, H Schwabl… - Behavioral …, 2018 - academic.oup.com
In males, testosterone plays a key role in ornament production and linking ornamentation
with reproductive behaviors and other traits to produce an integrated phenotype. Less is …

Social neuroendocrinology of status: A review and future directions

LD Hamilton, JM Carré, PH Mehta, N Olmstead… - … Human Behavior and …, 2015 - Springer
Status hierarchies are universal across human and non–human animal social groups.
Hormones and status interact with one another in a reciprocal manner. The present paper …

Beyond a biased binary: a perspective on the misconceptions, challenges, and implications of studying females in avian behavioral endocrinology

KO Smiley, SE Lipshutz, AA Kimmitt… - Frontiers in …, 2022 - frontiersin.org
For decades, avian endocrinology has been informed by male perspectives and male-
focused research, leaving significant gaps in our understanding of female birds. Male birds …

HormoneBase, a population-level database of steroid hormone levels across vertebrates

MN Vitousek, MA Johnson, JW Donald, CD Francis… - Scientific data, 2018 - nature.com
Hormones are central regulators of organismal function and flexibility that mediate a
diversity of phenotypic traits from early development through senescence. Yet despite these …

Androgenic signaling systems and their role in behavioral evolution

MJ Fuxjager, ER Schuppe - The Journal of steroid biochemistry and …, 2018 - Elsevier
Sex steroids mediate the organization and activation of masculine reproductive phenotypes
in diverse vertebrate taxa. However, the effects of sex steroid action in this context vary …