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Size-Dependent In Vivo Transport of Nanoparticles: Implications for Delivery, Targeting, and Clearance
Understanding the in vivo transport of nanoparticles provides guidelines for designing
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …
nanomedicines with higher efficacy and fewer side effects. Among many factors, the size of …
Ultrasmall coinage metal nanoclusters as promising theranostic probes for biomedical applications
Ultrasmall coinage metal nanoclusters (NCs,< 3 nm) have emerged as a novel class of
theranostic probes due to their atomically precise size and engineered physicochemical …
theranostic probes due to their atomically precise size and engineered physicochemical …
Antimicrobial nano-agents: the copper age
The constant advent of major health threats such as antibacterial resistance or highly
communicable viruses, together with a declining antimicrobial discovery, urgently requires …
communicable viruses, together with a declining antimicrobial discovery, urgently requires …
Transport and interactions of nanoparticles in the kidneys
Kidneys are a major organ for blood filtration and waste elimination and thus play a key role
in the transport and clearance of nanoparticles in vivo. The interactions of nanoparticles with …
in the transport and clearance of nanoparticles in vivo. The interactions of nanoparticles with …
Degradability and clearance of inorganic nanoparticles for biomedical applications
Inorganic nanoparticles with tunable and diverse properties hold tremendous potential in the
field of nanomedicine, while having non‐negligible toxicity concerns in healthy …
field of nanomedicine, while having non‐negligible toxicity concerns in healthy …
Physiological principles underlying the kidney targeting of renal nanomedicines
Kidney disease affects more than 10% of the global population and is associated with
considerable morbidity and mortality, highlighting a need for new therapeutic options …
considerable morbidity and mortality, highlighting a need for new therapeutic options …
Biodegradation-mediated enzymatic activity-tunable molybdenum oxide nanourchins for tumor-specific cascade catalytic therapy
Recent advances in nanomedicine have facilitated the development of potent nanomaterials
with intrinsic enzyme-like activities (nanozymes) for cancer therapy. However, it remains a …
with intrinsic enzyme-like activities (nanozymes) for cancer therapy. However, it remains a …
Clearance pathways and tumor targeting of imaging nanoparticles
A basic understanding of how imaging nanoparticles are removed from the normal
organs/tissues but retained in the tumors is important for their future clinical applications in …
organs/tissues but retained in the tumors is important for their future clinical applications in …
Copper sulfide nanoparticles as a photothermal switch for TRPV1 signaling to attenuate atherosclerosis
W Gao, Y Sun, M Cai, Y Zhao, W Cao, Z Liu… - Nature …, 2018 - nature.com
Atherosclerosis is characterized by the accumulation of lipids within the arterial wall.
Although activation of TRPV1 cation channels by capsaicin may reduce lipid storage and the …
Although activation of TRPV1 cation channels by capsaicin may reduce lipid storage and the …
Biocompatible semiconductor quantum dots as cancer imaging agents
Approximately 1.7 million new cases of cancer will be diagnosed this year in the United
States leading to 600 000 deaths. Patient survival rates are highly correlated with the stage …
States leading to 600 000 deaths. Patient survival rates are highly correlated with the stage …