Mansonellosis: current perspectives

TH Ta-Tang, JL Crainey, RJ Post, SLB Luz… - Research and reports …, 2018 - Taylor & Francis
Mansonellosis is a filarial disease caused by three species of filarial (nematode) parasites
(Mansonella perstans, Mansonella streptocerca, and Mansonella ozzardi) that use humans …

Mansonella ozzardi: a neglected New World filarial nematode

NF Lima, CA Veggiani Aybar… - … and Global Health, 2016 - Taylor & Francis
Mansonella ozzardi (Nematoda: Onchocercidae) is an understudied filarial nematode,
originally described by Patrick Manson in 1897, that can be transmitted by two families of …

Nested PCR to detect and distinguish the sympatric filarial species Onchocerca volvulus, Mansonella ozzardi and Mansonella perstans in the Amazon Region

THT Tang, R López-Vélez, M Lanza… - Memórias do Instituto …, 2010 - SciELO Brasil
We present filaria-nested polymerase chain reaction (PCR), which is based on amplification
of first internal transcribed spacer rDNA to distinguish three parasitic filarial species …

[HTML][HTML] Filarial disease in the Brazilian Amazon and emerging opportunities for treatment and control

CS Portela, CPM de Araújo, PM Sousa… - Current Research in …, 2024 - Elsevier
Following the successful eradication of Wuchereria bancrofti, there are now just three
species of conventional microfilaremic human filarial parasites endemic to the Brazilian …

A field trial of a PCR-based Mansonella ozzardi diagnosis assay detects high-levels of submicroscopic M. ozzardi infections in both venous blood samples and FTA® …

JF Medeiros, TAP Almeida, LBT Silva, JM Rubio… - Parasites & vectors, 2015 - Springer
Background Mansonella ozzardi is a poorly understood human filarial parasite with a broad
distribution throughout Latin America. Most of what is known about its parasitism has come …

New records of Mansonella ozzardi: a parasite that is spreading from the state of Amazonas to previously uninfected areas of the state of Acre in the Purus River …

YL Adami, G Rodrigues, MC Alves… - Memórias do Instituto …, 2013 - SciELO Brasil
Mansonella ozzardi infections are common in the riverside communities along the Solimões,
Negro and Purus Rivers in the state of Amazonas (AM). However, little is known about the …

Mansonella ozzardi in Amazonas, Brazil: prevalence and distribution in the municipality of Coari, in the middle Solimões River

M Martins, FAC Pessoa, MB Medeiros… - Memórias do Instituto …, 2010 - SciELO Brasil
This study investigated some epidemiological aspects of the Mansonella ozzardi in
municipality of Coari, Amazonas. Clinical symptoms were correlated with the filarial infection …

Survey of canine tick-borne diseases in Lábrea, Brazilian Amazon: 'accidental' findings of Dirofilaria immitis infection

HS Soares, LMA Camargo, SM Gennari… - Revista Brasileira de …, 2014 - SciELO Brasil
Blood samples were collected from 99 domestic dogs from the urban and rural areas of the
Lábrea municipality, state of Amazonas, Brazil. Canine serum samples were tested by …

CD39 and immune regulation in a chronic helminth infection: The puzzling case of Mansonella ozzardi

NF Lima, RM Goncalves-Lopes… - PLOS Neglected …, 2018 - journals.plos.org
Background Chronic helminth infections typically induce an immunoregulatory environment,
with markedly reduced immune responses to both parasite-specific and unrelated bystander …

Phase III clinical trial to evaluate ivermectin in the reduction of Mansonella ozzardi infection in the Brazilian Amazon

S de Almeida Basano, JSAA Camargo… - … American Journal of …, 2018 - pmc.ncbi.nlm.nih.gov
The treatment of mansonelliasis is still a challenge because there are few clinical trials for
the treatment of the disease. This double-blind, randomized, placebo-controlled study …