Apoptosis and necroptosis in the liver: a matter of life and death

RF Schwabe, T Luedde - Nature reviews Gastroenterology & …, 2018 - nature.com
Cell death represents a basic biological paradigm that governs outcomes and long-term
sequelae in almost every hepatic disease condition. Acute liver failure is characterized by …

[HTML][HTML] Pyroptosis in liver disease: new insights into disease mechanisms

J Wu, S Lin, B Wan, B Velani, Y Zhu - Aging and disease, 2019 - ncbi.nlm.nih.gov
There has been increasing interest in pyroptosis as a novel form of pro-inflammatory
programmed cell death. The mechanism of pyroptosis is significantly different from other …

Role of mitochondrial pathways in cell apoptosis during He-patic ischemia/reperfusion injury

S Zhang, S Rao, M Yang, C Ma, F Hong… - International journal of …, 2022 - mdpi.com
Hepatic ischemia-reperfusion injury is a major cause of post-operative hepatic dysfunction
and liver failure after transplantation. Mitochondrial pathways can be either beneficial or …

Curcumin-loaded chitosan nanoparticles alleviate fenpropathrin-induced hepatotoxicity by regulating lipogenesis and pyroptosis in rats

LS Alqahtani, YM Abd-Elhakim, AAR Mohamed… - Food and Chemical …, 2023 - Elsevier
In this study, the probable alleviative role of curcumin (CMN)(50 mg/kg b. wt) or curcumin-
loaded chitosan nanoparticle (CLC-NP)(50 mg/kg b. wt) was assessed against the …

[HTML][HTML] Protective effects of Cinnamomum zeylanicum L.(Darchini) in acetaminophen-induced oxidative stress, hepatotoxicity and nephrotoxicity in mouse model

Z Hussain, JA Khan, A Arshad, P Asif, H Rashid… - Biomedicine & …, 2019 - Elsevier
Cinnamomum zeylanicum, a widely used spice and flavor, is used in the treatment and
prevention of many diseases. In the current study, Balb/c mice were pretreated with …

Adiponectin and PPAR: a setup for intricate crosstalk between obesity and non-alcoholic fatty liver disease

SM Ishtiaq, H Rashid, Z Hussain, MI Arshad… - Reviews in Endocrine …, 2019 - Springer
Adiponectin, a soluble adipocytokine, plays an important role in the functioning of adipose
tissue and in the regulation of inflammation, particularly hepatic inflammation. The …

Antioxidant nanozymes as next-generation therapeutics to free radical-mediated inflammatory diseases: A comprehensive review

S Singh - International Journal of Biological Macromolecules, 2024 - Elsevier
Recent developments in exploring the biological enzyme mimicking properties in
nanozymes have opened a separate avenue, which provides a suitable alternative to the …

Corilagin ameliorates con A-induced hepatic injury by restricting M1 macrophage polarization

F Yan, D Cheng, H Wang, M Gao, J Zhang… - Frontiers in …, 2022 - frontiersin.org
Immune-mediated hepatic injury plays a key role in the initiation and pathogenesis of
diverse liver diseases. However, treatment choice for immune-mediated hepatic injury …

An overview of hepatocellular carcinoma after insufficient radiofrequency ablation

Y Guo, Y Ren, X Dong, X Kan… - Journal of Hepatocellular …, 2022 - Taylor & Francis
Radiofrequency ablation (RFA) is a commonly used treatment for hepatocellular carcinoma
(HCC), however, various complex conditions in clinical practice may lead to insufficient …

[Retracted] Preventive Effects of Mandarin Fruit Peel Hydroethanolic Extract, Hesperidin, and Quercetin on Acetaminophen‐Induced Hepatonephrotoxicity in Wistar …

DN Eldin, HI Fahim, HY Ahmed… - Oxidative Medicine …, 2022 - Wiley Online Library
Acetaminophen, also known as N‐acetyl‐para‐aminophenol (NAPAP), is a traditional
antipyretic and analgesic that is used extensively around the world to treat colds and fevers …