Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria

JG Beeson, DR Drew, MJ Boyle, G Feng… - FEMS microbiology …, 2016 - academic.oup.com
Malaria accounts for an enormous burden of disease globally, with Plasmodium falciparum
accounting for the majority of malaria, and P. vivax being a second important cause …

The molecular basis of erythrocyte invasion by malaria parasites

AF Cowman, CJ Tonkin, WH Tham, MT Duraisingh - Cell host & microbe, 2017 - cell.com
Plasmodium species cause malaria by proliferating in human erythrocytes. Invasion of
immunologically privileged erythrocytes provides a relatively protective niche as well as …

[HTML][HTML] Functional profiling of a Plasmodium genome reveals an abundance of essential genes

E Bushell, AR Gomes, T Sanderson, B Anar, G Girling… - Cell, 2017 - cell.com
The genomes of malaria parasites contain many genes of unknown function. To assist drug
development through the identification of essential genes and pathways, we have measured …

Revealing the Sequence and Resulting Cellular Morphology of Receptor-Ligand Interactions during Plasmodium falciparum Invasion of Erythrocytes

GE Weiss, PR Gilson, T Taechalertpaisarn… - PLoS …, 2015 - journals.plos.org
During blood stage Plasmodium falciparum infection, merozoites invade uninfected
erythrocytes via a complex, multistep process involving a series of distinct receptor-ligand …

The cellular and molecular basis for malaria parasite invasion of the human red blood cell

AF Cowman, D Berry, J Baum - Journal of cell Biology, 2012 - rupress.org
Malaria is a major disease of humans caused by protozoan parasites from the genus
Plasmodium. It has a complex life cycle; however, asexual parasite infection within the blood …

Computational improvements reveal great bacterial diversity and high metal toxicity in soil

J Gans, M Wolinsky, J Dunbar - Science, 2005 - science.org
The complexity of soil bacterial communities has thus far confounded effective
measurement. However, with improved analytical methods, we show that the abundance …

Invasion of red blood cells by malaria parasites

AF Cowman, BS Crabb - Cell, 2006 - cell.com
The malaria parasite is the most important member of the Apicomplexa, a large and highly
successful phylum of intracellular parasites. Invasion of host cells allows apicomplexan …

Essential role of the PfRh5/PfRipr/CyRPA complex during Plasmodium falciparum invasion of erythrocytes

JC Volz, A Yap, X Sisquella, JK Thompson, NTY Lim… - Cell host & …, 2016 - cell.com
Plasmodium falciparum parasites in the merozoite stage invade human erythrocytes and
cause malaria. Invasion requires multiple interactions between merozoite ligands and …

Comparative genomics of the neglected human malaria parasite Plasmodium vivax

JM Carlton, JH Adams, JC Silva, SL Bidwell, H Lorenzi… - Nature, 2008 - nature.com
The human malaria parasite Plasmodium vivax is responsible for 25–40% of the∼ 515
million annual cases of malaria worldwide. Although seldom fatal, the parasite elicits severe …

[HTML][HTML] Super-resolution dissection of coordinated events during malaria parasite invasion of the human erythrocyte

DT Riglar, D Richard, DW Wilson, MJ Boyle… - Cell host & …, 2011 - cell.com
Erythrocyte invasion by the merozoite is an obligatory stage in Plasmodium parasite
infection and essential to malaria disease progression. Attempts to study this process have …