The approval of anticancer therapeutic strategies is still slowed down by the lack of models
able to faithfully reproduce in vivo cancer physiology. On one hand, the conventional in vitro …

Microphysiological systems (MPS), also known as Organ (s)-on-Chip (OoC), are in vitro cell
culture platforms that reproduce the function of cells/tissues/organs in a microenvironment …

With the rapid development and commercial interest in the organ-on-a-chip (OoC) field,
there is a need for materials addressing key experimental demands and enabling both …

Microfluidics evolved with the appearance of polydimethylsiloxane (PDMS), an elastomer
with a short processing time and the possibility for replication on a micrometric scale …

Abstract The recent US FDA Modernization Act 2.0 has intensified interest in microfluidic-
based in vitro systems for preclinical research. However, the high costs of conventional …

Recent advancements in vascular organoid (VO) and vessel-on-chip (VoC) technologies
have revolutionized our approach to studying human diseases, offering unprecedented …

Organ-on-a-chip (OoC) is a breakthrough technology in biomedicine. As a
microphysiological system constructed in vitro, OoCs can simulate the main structures and …

Spermatogenesis is one of the most complex processes of cell differentiation and its failure
is a major cause of male infertility. Therefore, a proper model that recapitulates …

In light of the emerging breakthroughs in cancer biology, drug discovery, and personalized
medicine, Tumor-on-Chip (ToC) platforms have become pivotal tools in current biomedical …

Microphysiological systems (MPS) and Organs-on-Chips (OoCs) hold significant potential
for replicating complex human biological processes in vitro. However, their widespread …