Zinc oxide (ZnO) is an adaptable material that has distinctive properties, such as high-
sensitivity, large specific area, non-toxicity, good compatibility and a high isoelectric point …

Oligomers which form during amyloid fibril assembly are considered to be key contributors
towards amyloid disease. However, understanding how such intermediates form, their …

In this approach, zinc oxide (ZnO) is a multipurpose substance with remarkable
characteristics such as high sensitivity, a large specific area, non‐toxicity, excellent …

Single-molecule force spectroscopy makes it possible to measure the mechanical strength
of single noncovalent receptor-ligand-type bonds. A major challenge in this technique is to …

Elucidating the molecular mechanisms in the development of such a devastating
neurodegenerative disorder as Alzheimer's disease (AD) is currently one of the major …

Over the past few decades, single-molecule manipulation has been widely applied to the
real-time analysis of biomolecular interactions. It has enabled researchers to decipher …

In neurodegenerative diseases, a wide range of amyloid proteins or peptides such as
amyloid-beta and α-synuclein fail to keep native functional conformations, followed by …

Soluble amyloid-beta (Aβ) oligomers are the prime causative agents of cognitive deficits
during early stages of Alzheimer's disease (AD). The transient nature of the oligomers …

The ability of biophysicists to decipher the behavior of individual biomolecules has steadily
improved over the past thirty years. However, it still remains unclear how an ensemble of …

Protein aggregation is linked with the onset of several neurodegenerative disorders,
including Parkinson's disease (PD), which is associated with the aggregation of α‐synuclein …