Structural and functional aspects of Ebola virus proteins

S Jain, E Martynova, A Rizvanov, S Khaiboullina… - Pathogens, 2021 - mdpi.com
Ebola virus (EBOV), member of genus Ebolavirus, family Filoviridae, have a non-segmented,
single-stranded RNA that contains seven genes:(a) nucleoprotein (NP),(b) viral protein 35 …

Immune correlates of protection for SARS-CoV-2, Ebola and Nipah virus infection

B Escudero-Pérez, P Lawrence… - Frontiers in …, 2023 - frontiersin.org
Correlates of protection (CoP) are biological parameters that predict a certain level of
protection against an infectious disease. Well-established correlates of protection facilitate …

Single-cell profiling of lncRNA expression during Ebola virus infection in rhesus macaques

L Santus, M Sopena-Rios, R García-Pérez… - Nature …, 2023 - nature.com
Long non-coding RNAs (lncRNAs) are involved in numerous biological processes and are
pivotal mediators of the immune response, yet little is known about their properties at the …

Epidemiology of ebolaviruses from an etiological perspective

S Jain, S Khaiboullina, E Martynova, S Morzunov… - Pathogens, 2023 - mdpi.com
Since the inception of the ebolavirus in 1976, 32 outbreaks have resulted in nearly 15,350
deaths in more than ten countries of the African continent. In the last decade, the largest …

How to prepare for the next inevitable Ebola outbreak: lessons from West Africa

HK Bosa, N Kamara, M Aragaw, M Wayengera… - Nature Medicine, 2024 - nature.com
How to prepare for the next inevitable Ebola outbreak: lessons from West Africa | Nature
Medicine Skip to main content Thank you for visiting nature.com. You are using a browser …

Single-dose VSV-based vaccine protects cynomolgus macaques from disease after Tai Forest virus infection

P Fletcher, KL O'Donnell, BM Doratt… - Emerging Microbes & …, 2023 - Taylor & Francis
Taï Forest virus (TAFV) is a lesser-known ebolavirus that causes lethal infections in
chimpanzees and is responsible for a single human case. Limited research has been done …

[HTML][HTML] Treatment of Acute and Long-COVID, Diabetes, Myocardial Infarction, and Alzheimer's Disease: The Potential Role of a Novel Nano-Compound—The …

R Yutani, V Venketaraman, N Sheren - Antioxidants, 2024 - mdpi.com
Oxidative stress (OS) occurs from excessive reactive oxygen species or a deficiency of
antioxidants—primarily endogenous glutathione (GSH). There are many illnesses, from …

Pathogenic differences of cynomolgus macaques after Taï Forest virus infection depend on the viral stock propagation

P Fletcher, CS Clancy, KL O'Donnell, BM Doratt… - PLoS …, 2024 - journals.plos.org
Taï Forest virus (TAFV) is a negative-sense RNA virus in the Filoviridae family. TAFV has
caused only a single human infection, but several disease outbreaks in chimpanzees have …

Remdesivir is efficacious in rhesus monkeys exposed to aerosolized Ebola virus

TK Warren, CD Kane, J Wells, KS Stuthman… - Scientific Reports, 2021 - nature.com
Efficacious therapeutics for Ebola virus disease are in great demand. Ebola virus infections
mediated by mucosal exposure, and aerosolization in particular, present a novel challenge …

Antiinflammatory phytochemicals against virus‐induced hyperinflammatory responses: Scope, rationale, application, and limitations

M Baranwal, Y Gupta, P Dey… - Phytotherapy Research, 2021 - Wiley Online Library
Uncontrolled inflammatory responses or cytokine storm associated with viral infections
results in deleterious consequences such as vascular leakage, severe hemorrhage, shock …