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Chagas disease: an overview of clinical and epidemiological aspects
Chagas disease, caused by the parasite Trypanosoma cruzi, is a serious health problem in
Latin America and is an emerging disease in non-endemic countries. In recent decades, the …
Latin America and is an emerging disease in non-endemic countries. In recent decades, the …
Chagas disease cardiomyopathy: immunopathology and genetics
Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in Latin America
and affects ca. 10 million people worldwide. About 30% of Chagas disease patients develop …
and affects ca. 10 million people worldwide. About 30% of Chagas disease patients develop …
The endless race between Trypanosoma cruzi and host immunity: lessons for and beyond Chagas disease
Infection with the protozoan parasite Trypanosoma cruzi, the agent of Chagas disease, is
characterised by a variable clinical course–from symptomless cases to severe chronic …
characterised by a variable clinical course–from symptomless cases to severe chronic …
Chemokines, inflammation and Trypanosoma cruzi infection
The inflammatory response that follows the infection with Trypanosoma cruzi is essential for
host resistance to infection but is also responsible for the diverse pathology observed in …
host resistance to infection but is also responsible for the diverse pathology observed in …
[HTML][HTML] Autoimmune pathogenesis of Chagas heart disease: looking back, looking ahead
KM Bonney, DM Engman - The American journal of pathology, 2015 - Elsevier
Chagas heart disease is an inflammatory cardiomyopathy that develops in approximately
one-third of individuals infected with the protozoan parasite Trypanosoma cruzi. Since the …
one-third of individuals infected with the protozoan parasite Trypanosoma cruzi. Since the …
Disease Tolerance and Pathogen Resistance Genes May Underlie Trypanosoma cruzi Persistence and Differential Progression to Chagas Disease Cardiomyopathy
Chagas disease is caused by infection with the protozoan Trypanosoma cruzi and affects
over 8 million people worldwide. In spite of a powerful innate and adaptive immune …
over 8 million people worldwide. In spite of a powerful innate and adaptive immune …
Myocardial Chemokine Expression and Intensity of Myocarditis in Chagas Cardiomyopathy Are Controlled by Polymorphisms in CXCL9 and CXCL10
LG Nogueira, RHB Santos, BM Ianni… - PLoS Neglected …, 2012 - journals.plos.org
Background Chronic Chagas cardiomyopathy (CCC), a life-threatening inflammatory dilated
cardiomyopathy, affects 30% of the approximately 8 million patients infected by …
cardiomyopathy, affects 30% of the approximately 8 million patients infected by …
Cytokine networks as targets for preventing and controlling Chagas heart disease
CC Koh, EGA Neves, TG de Souza-Silva, AC Carvalho… - Pathogens, 2023 - mdpi.com
Chagas disease, a neglected disease caused by the protozoan Trypanosoma cruzi, is
endemic in 21 Latin American countries, affecting 6–8 million people. Increasing numbers of …
endemic in 21 Latin American countries, affecting 6–8 million people. Increasing numbers of …
CCR5 Plays a Critical Role in the Development of Myocarditis and Host Protection in Mice Infected with Trypanosoma cruzi
The pathogenesis of myocarditis during Trypanosoma cruzi infection is poorly understood.
We investigated the role played by chemokine receptor 5 (CCR5) in the influx of T cells to …
We investigated the role played by chemokine receptor 5 (CCR5) in the influx of T cells to …
The determinants of Chagas disease: connecting parasite and host genetics
DA Campbell, SJ Westenberger… - Current molecular …, 2004 - ingentaconnect.com
As a consequence of infection by Trypanosoma cruzi, 30% of victims may develop chronic
Chagas disease, which presents a spectrum of pathology including cardiomyopathy …
Chagas disease, which presents a spectrum of pathology including cardiomyopathy …