Nonsense-mediated mRNA decay (NMD) is arguably the best-studied eukaryotic
messenger RNA (mRNA) surveillance pathway, yet fundamental questions concerning the …

Nonsense-mediated mRNA decay is a eukaryotic pathway that degrades transcripts with
premature termination codons (PTCs). In most eukaryotes, thousands of transcripts are …

Nonsense‐mediated mRNA decay (NMD) is a translation‐dependent RNA degradation
pathway involved in many cellular pathways and crucial for telomere maintenance and …

Summary The RNA helicase UP‐FRAMESHIFT (UPF1) is a key factor of nonsense‐
mediated decay (NMD), a mRNA decay pathway involved in RNA quality control and in the …

Nonsense-mediated RNA decay (NMD) plays a dual role as an RNA surveillance
mechanism against aberrant transcripts containing premature termination codons and as a …

The presence of premature termination codons (PTCs) in transcripts is dangerous for the cell
as they encode potentially deleterious truncated proteins that can act with dominant …

Although most species have two sexes, multisexual (or multi-mating type) species are also
widespread. However, it is unclear how mating-type recognition is achieved at the molecular …

The virus–host interaction is dynamic and evolutionary. Viruses have to fight with hosts to
establish successful infection. Eukaryotic hosts are equipped with multiple defenses against …

Nonsense-mediated decay (NMD) is a conserved mRNA quality control process that
eliminates transcripts bearing a premature termination codon. In addition to its role in …

Nonsense-mediated mRNA decay (NMD) is important for RNA quality control and gene
regulation in eukaryotes. NMD targets aberrant transcripts for decay and also directly …