An organismal understanding of C. elegans innate immune responses, from pathogen recognition to multigenerational resistance

TD Tran, RJ Luallen - Seminars in cell & developmental biology, 2024 - Elsevier
The nematode Caenorhabditis elegans has been a model for studying infection since the
early 2000s and many major discoveries have been made regarding its innate immune …

Host and microbiome jointly contribute to environmental adaptation

C Petersen, IK Hamerich, KL Adair… - The ISME …, 2023 - academic.oup.com
Most animals and plants have associated microorganisms, collectively referred to as their
microbiomes, which can provide essential functions. Given their importance, host-associated …

Nuclear hormone receptor NHR-49 is an essential regulator of stress resilience and healthy aging in Caenorhabditis elegans

KRS Doering, G Ermakova, S Taubert - Frontiers in Physiology, 2023 - frontiersin.org
The genome of Caenorhabditis elegans encodes 284 nuclear hormone receptor, which
perform diverse functions in development and physiology. One of the best characterized of …

Exploring Effects of C. elegans Protective Natural Microbiota on Host Physiology

KAB Kissoyan, L Peters, C Giez, J Michels… - Frontiers in Cellular …, 2022 - frontiersin.org
The Caenorhabditis elegans natural microbiota was described only recently. Thus, our
understanding of its effects on nematode physiology is still in its infancy. We previously …

The Caenorhabditis elegans proteome response to two protective Pseudomonas symbionts

B Pees, L Peters, C Treitz, IK Hamerich, KAB Kissoyan… - Mbio, 2024 - journals.asm.org
The Caenorhabditis elegans natural microbiota isolates Pseudomonas lurida MYb11 and
Pseudomonas fluorescens MYb115 protect the host against pathogens through distinct …

Spatiotemporal Tracking of Near‐Infrared Fluorescent Single‐Walled Carbon Nanotubes in C. Elegans Nematodes Confined in a Microfluidics Platform

E Sharaga, A Hendler‐Neumark… - Advanced Materials …, 2024 - Wiley Online Library
Caenorhabditis elegans (C. elegans) nematodes are a powerful model organism for diverse
biological and biomedical studies, benefiting from their genetic similarities to humans, small …

[HTML][HTML] Omics approaches to investigate the neuroprotective capacity of a Citrus sinensis (sweet orange) extract in a Caenorhabditis elegans Alzheimer's model

JD Sánchez-Martínez, A Cifuentes, A Valdés - Food Research International, 2023 - Elsevier
Citrus sinensis by-products are a promising source of neuroprotective molecules. In this
study, a pressurized liquid extract of Citrus by-products (PLE100) has been extensively …

Story of an infection: Viral dynamics and host responses in the Caenorhabditis elegans–Orsay virus pathosystem

VG Castiglioni, MJ Olmo-Uceda, A Villena-Giménez… - Science …, 2024 - science.org
Orsay virus (OrV) is the only known natural virus affecting Caenorhabditis elegans, with
minimal impact on the animal's fitness due to its robust innate immune response. This study …

The matrisome landscape controlling in vivo germ cell fates

A Amran, L Pigatto, J Farley, R Godini… - Nature …, 2024 - nature.com
The developmental fate of cells is regulated by intrinsic factors and the extracellular
environment. The extracellular matrix (matrisome) delivers chemical and mechanical cues …

Protein Diversity and Immune Specificity of Hemocyanin From Shrimp Litopenaeus vannamei

X Zhao, J Qiao, P Zhang, Z Zhang, JJ Aweya… - Frontiers in …, 2021 - frontiersin.org
Hemocyanin is an important non-specific innate immune defense molecule with
phenoloxidase, antiviral, antibacterial, hemolytic, and antitumor activities. To better …