Restoring brain function after stroke—bridging the gap between animals and humans

NS Ward - Nature Reviews Neurology, 2017 - nature.com
Stroke is the leading cause of complex adult disability in the world. Recovery from stroke is
often incomplete, which leaves many people dependent on others for their care. The …

The human motor cortex microcircuit: insights for neurodegenerative disease

P McColgan, J Joubert, SJ Tabrizi… - Nature Reviews …, 2020 - nature.com
The human motor cortex comprises a microcircuit of five interconnected layers with different
cell types. In this Review, we use a layer-specific and cell-specific approach to integrate …

The phase of sensorimotor mu and beta oscillations has the opposite effect on corticospinal excitability

M Wischnewski, ZJ Haigh, S Shirinpour, I Alekseichuk… - Brain stimulation, 2022 - Elsevier
Background Neural oscillations in the primary motor cortex (M1) shape corticospinal
excitability. Power and phase of ongoing mu (8–13 Hz) and beta (14–30 Hz) activity may …

[HTML][HTML] I overthink—Therefore I am not: An active inference account of altered sense of self and agency in depersonalisation disorder

A Ciaunica, A Seth, J Limanowski, C Hesp… - Consciousness and …, 2022 - Elsevier
This paper considers the phenomenology of depersonalisation disorder, in relation to
predictive processing and its associated pathophysiology. To do this, we first establish a few …

Altered effective connectivity in sensorimotor cortices is a signature of severity and clinical course in depression

D Ray, D Bezmaternykh, M Mel'nikov, KJ Friston… - Proceedings of the …, 2021 - pnas.org
Functional neuroimaging research on depression has traditionally targeted neural networks
associated with the psychological aspects of depression. In this study, instead, we focus on …

Ten problems and solutions when predicting individual outcome from lesion site after stroke

CJ Price, TM Hope, ML Seghier - Neuroimage, 2017 - Elsevier
In this paper, we consider solutions to ten of the challenges faced when trying to predict an
individual's functional outcome after stroke on the basis of lesion site. A primary goal is to …

GABAergic cortical network physiology in frontotemporal lobar degeneration

NE Adams, LE Hughes, MA Rouse, HN Phillips… - Brain, 2021 - academic.oup.com
The clinical syndromes caused by frontotemporal lobar degeneration are heterogeneous,
including the behavioural variant frontotemporal dementia (bvFTD) and progressive …

Reorganization of cortical oscillatory dynamics underlying disinhibition in frontotemporal dementia

LE Hughes, T Rittman, TW Robbins, JB Rowe - Brain, 2018 - academic.oup.com
The distribution of pathology in frontotemporal dementia is anatomically selective, to distinct
cortical regions and with differential neurodegeneration across the cortical layers. The …

[HTML][HTML] Generic dynamic causal modelling: An illustrative application to Parkinson's disease

BCM van Wijk, H Cagnan, V Litvak, AA Kühn… - NeuroImage, 2018 - Elsevier
We present a technical development in the dynamic causal modelling of
electrophysiological responses that combines qualitatively different neural mass models …

Therapeutic applications of BCI technologies

DJ McFarland, J Daly, C Boulay… - Brain-Computer …, 2017 - Taylor & Francis
Brain-computer interface (BCI) technology can restore communication and control to people
who are severely paralyzed. There has been speculation that this technology might also be …