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[HTML][HTML] The complement system, aging, and aging-related diseases
R Zheng, Y Zhang, K Zhang, Y Yuan, S Jia… - International Journal of …, 2022 - mdpi.com
The complement system is a part of the immune system and consists of multiple complement
components with biological functions such as defense against pathogens and …
components with biological functions such as defense against pathogens and …
Targeting epigenetics: a novel promise for Alzheimer's disease treatment
So far, the search for a cure for Alzheimer Disease (AD) has been unsuccessful. The only
approved drugs attenuate some symptoms, but do not halt the progress of this disease …
approved drugs attenuate some symptoms, but do not halt the progress of this disease …
Integrated multi-omics analysis of Alzheimer's disease shows molecular signatures associated with disease progression and potential therapeutic targets
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by the
formation of amyloid plaques implicated in neuronal death. Genetics, age, and sex are the …
formation of amyloid plaques implicated in neuronal death. Genetics, age, and sex are the …
Study on the Role of an Erythrocyte Membrane‐Coated Nanotheranostic System in Targeted Immune Regulation of Alzheimer's Disease
Y Su, Y Huang, Q Kou, L Lu, H Jiang, X Li… - Advanced …, 2023 - Wiley Online Library
Alzheimer's disease (AD) is one of the most common neurodegenerative diseases in the
elderly population. Despite significant advances in studies of the pathobiology on AD, there …
elderly population. Despite significant advances in studies of the pathobiology on AD, there …
[HTML][HTML] Innate immunity: a balance between disease and adaption to stress
I Faenza, WL Blalock - Biomolecules, 2022 - mdpi.com
Since first being documented in ancient times, the relation of inflammation with injury and
disease has evolved in complexity and causality. Early observations supported a cause …
disease has evolved in complexity and causality. Early observations supported a cause …
The human factor H protein family–an update
Complement is an ancient and complex network of the immune system and, as such, it plays
vital physiological roles, but it is also involved in numerous pathological processes. The …
vital physiological roles, but it is also involved in numerous pathological processes. The …
The specific mechanism of TREM2 regulation of synaptic clearance in Alzheimer's disease
Q Qin, M Wang, Y Yin, Y Tang - Frontiers in Immunology, 2022 - frontiersin.org
Alzheimer's disease (AD) is a progressive neurodegenerative disease. Synaptic dysfunction
is an integral feature of AD pathophysiology and a significant factor in early cognitive …
is an integral feature of AD pathophysiology and a significant factor in early cognitive …
Neuroprotection of low-molecular-weight galactan obtained from Cantharellus cibarius Fr. against Alzheimer's disease
A Zhou, H Cheng, H Liu, L Li, Z Chen, S Chen… - Carbohydrate …, 2023 - Elsevier
The large molecular weight of polysaccharides limits their absorption and utilization by
organisms, affecting their biological activities. In this study, we purified α-1, 6-galactan from …
organisms, affecting their biological activities. In this study, we purified α-1, 6-galactan from …
Probing Protein Structural Changes in Alzheimer's Disease via Quantitative Cross-linking Mass Spectrometry
Alzheimer's disease (AD) is a progressive neurological disorder featuring abnormal protein
aggregation in the brain, including the pathological hallmarks of amyloid plaques and …
aggregation in the brain, including the pathological hallmarks of amyloid plaques and …
The diverse roles of reactive astrocytes in the pathogenesis of amyotrophic lateral sclerosis
K Yang, Y Liu, M Zhang - Brain Sciences, 2024 - mdpi.com
Astrocytes displaying reactive phenotypes are characterized by their ability to remodel
morphologically, molecularly, and functionally in response to pathological stimuli. This …
morphologically, molecularly, and functionally in response to pathological stimuli. This …