Plants have long been exploited as a sustainable source of food, flavors, agrochemicals,
colors, therapeutic proteins, bioactive compounds, and stem cell production. However, plant …

In this review, we address recent advances made in pathway engineering, directed
evolution, and systems/synthetic biology approaches employed in the production and …

Highlights•Microbial cell factories are becoming important in sustainable chemical
production.•Systems metabolic engineering allows efficient microbial cell factory …

Engineering Plant Secondary Metabolism in Microbial Systems | Plant Physiology | Oxford
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Hydroxypropionic acid (3HP), an important three carbon (C3) chemical, is designated as
one of the top platform chemicals with an urgent need for improved industrial production …

Phenolics are a class of plant-derived natural secondary metabolites with good anticancer,
anti-inflammatory, antimicrobial and antioxidant activities. In addition to being natural health …

Covering: 1976 to 2020. Although constituting a limited chemical family, phytostilbenes
represent an emblematic group of molecules among natural compounds. Ever since their …

Malonyl-CoA is an important central metabolite for the production of diverse valuable
chemicals including natural products, but its intracellular availability is often limited due to …

Metabolic heterogeneity and dynamic changes in metabolic fluxes are two inherent
characteristics of microbial fermentation that limit the precise control of metabolisms, often …

Corynebacterium glutamicum is an important organism in industrial biotechnology for the
microbial production of bulk chemicals, in particular amino acids. However, until now activity …