Background Emerging fungal pathogens pose important threats to global public health. The
World Health Organization has responded to the rising threat of traditionally neglected …

Invasive candidiasis (IC) is a leading cause of mycosis-associated mortality in the United
States. We examined data from the National Center for Health Statistics and reviewed recent …

Antifungal susceptibility testing of Candida has been standardized and refined and now may
play a useful role in managing Candida infections. Important new developments include …

Candida species are the most common cause of fungal infections. Candida species produce
infections that range from non—life-threatening mucocutaneous illnesses to invasive …

A substantial proportion of patients become colonised with Candida spp during hospital
stay, but only few subsequently develop severe infection. Clinical signs of severe infection …

Biofilms, likely the predominant mode of device-related microbial infection, exhibit resistance
to antimicrobial agents. Evidence suggests that Candida biofilms have dramatically reduced …

Candida albicans and related species pathogenic for man become resistant to antifungal
agents, in particular triazole compounds, by expression of efflux pumps that reduce drug …

Voriconazole is the first available second-generation triazole with potent activity against a
broad spectrum of clinically significant fungal pathogens, including Aspergillus, Candida …

ABSTRACT The SENTRY Antimicrobial Surveillance Program monitors global susceptibility
and resistance rates of newer and established antifungal agents. We report the …

Invasive fungal infections are an important cause of human mortality and morbidity,
particularly for immunocompromised populations. However, there remains a paucity of …