[HTML][HTML] Micro and Nanofabrication methods to control cell-substrate interactions and cell behavior: A review from the tissue engineering perspective

M Ermis, E Antmen, V Hasirci - Bioactive materials, 2018 - Elsevier
Cell-substrate interactions play a crucial role in the design of better biomaterials and
integration of implants with the tissues. Adhesion is the binding process of the cells to the …

Micropillars in biomechanics: Role in guiding mesenchymal stem cells differentiation and bone regeneration

Y Long, Y Sun, L **, Y Qin… - Advanced Materials …, 2024 - Wiley Online Library
Efficient bone repair relies on biomaterials that exhibit superior biocompatibility and
enhanced osteogenic capabilities. In recent, micropatterning technology has emerged as a …

A high-throughput microfabricated platform for rapid quantification of metastatic potential

S Bhattacharya, A Ettela, J Haydak, CM Hobson… - Science …, 2024 - science.org
Assays that measure morphology, proliferation, motility, deformability, and migration are
used to study the invasiveness of cancer cells. However, native invasive potential of cells …

Biofabrication of aligned structures that guide cell orientation and applications in tissue engineering

K Lu, Y Qian, J Gong, Z Zhu, J Yin, L Ma, M Yu… - Bio-Design and …, 2021 - Springer
The organized alignment of cells in various tissues plays a significant role in the
maintenance of specific functions. To induce such an alignment, ideal scaffolds should …

Fabrication and applications of stimuli‐responsive micro/nanopillar arrays

JE Park, S Won, W Cho, JG Kim… - Journal of Polymer …, 2021 - Wiley Online Library
The functional surface features of living creatures are driven by the complex morphology of
periodically arranged micro/nanoscale structures. Various fabrication processes have been …

Cell engineering: biophysical regulation of the nucleus

Y Song, J Soto, B Chen, L Yang, S Li - Biomaterials, 2020 - Elsevier
Cells live in a complex and dynamic microenvironment, and a variety of microenvironmental
cues can regulate cell behavior. In addition to biochemical signals, biophysical cues can …

Role of the nucleus as a sensor of cell environment topography

K Anselme, NT Wakhloo, P Rougerie… - Advanced healthcare …, 2018 - Wiley Online Library
The proper integration of biophysical cues from the cell vicinity is crucial for cells to maintain
homeostasis, cooperate with other cells within the tissues, and properly fulfill their biological …

Mechanochemical patternable ECM‐mimetic hydrogels for programmed cell orientation

P Lavrador, VM Gaspar, JF Mano - Advanced Healthcare …, 2020 - Wiley Online Library
Native human tissues are supported by a viscoelastic extracellular matrix (ECM) that can
adapt its intricate network to dynamic mechanical stimuli. To recapitulate the unique ECM …

Nonmonotonic self-deformation of cell nuclei on topological surfaces with micropillar array

X Liu, R Liu, Y Gu, J Ding - ACS Applied Materials & Interfaces, 2017 - ACS Publications
Cells respond to the mechanical signals from their surroundings and integrate
physiochemical signals to initiate intricate mechanochemical processes. While many studies …

Dynamic adaptation of mesenchymal stem cell physiology upon exposure to surface micropatterns

NRM Beijer, ZM Nauryzgaliyeva, EM Arteaga… - Scientific reports, 2019 - nature.com
Human mesenchymal stem (hMSCs) are defined as multi-potent colony-forming cells
expressing a specific subset of plasma membrane markers when grown on flat tissue culture …