Burkholderia pseudomallei and melioidosis
Burkholderia pseudomallei, the causative agent of melioidosis, is found in soil and water of
tropical and subtropical regions globally. Modelled estimates of the global burden predict …
tropical and subtropical regions globally. Modelled estimates of the global burden predict …
Antimicrobial peptides: from design to clinical application
Infection of multidrug-resistant (MDR) bacteria, such as methicillin-resistant Staphylococcus
aureus (MRSA), carbapenem-resistant Enterobacteriaceae (CRE), and extended-spectrum …
aureus (MRSA), carbapenem-resistant Enterobacteriaceae (CRE), and extended-spectrum …
Genetically diverse Pseudomonas aeruginosa populations display similar transcriptomic profiles in a cystic fibrosis explanted lung
Previous studies have demonstrated substantial genetic diversification of Pseudomonas
aeruginosa across sub-compartments in cystic fibrosis (CF) lungs. Here, we isolate P …
aeruginosa across sub-compartments in cystic fibrosis (CF) lungs. Here, we isolate P …
[PDF][PDF] Antibiotic susceptibility of clinical Burkholderia pseudomallei isolates in northeast Thailand during 2015-2018 and the genomic characterization of β-lactam …
Melioidosis is an often fatal infection in tropical regions caused by an environmental
bacterium, Burkholderia pseudomallei. Current recommended melioidosis treatment …
bacterium, Burkholderia pseudomallei. Current recommended melioidosis treatment …
Effective therapeutic options for melioidosis: antibiotics versus phage therapy
YM Lim, J Vadivelu, V Mariappan, G Venkatraman… - Pathogens, 2022 - mdpi.com
Melioidosis, also known as Whitmore's disease, is a potentially fatal infection caused by the
Gram-negative bacteria Burkholderia pseudomallei with a mortality rate of 10–50%. The …
Gram-negative bacteria Burkholderia pseudomallei with a mortality rate of 10–50%. The …
Raising the Stakes: Loss of Efflux Pump Regulation Decreases Meropenem Susceptibility in Burkholderia pseudomallei
DS Sarovich, JR Webb, MC Pitman… - Clinical Infectious …, 2018 - academic.oup.com
Background Burkholderia pseudomallei, the causative agent of the high-mortality disease
melioidosis, is a gram-negative bacterium that is naturally resistant to many antibiotics …
melioidosis, is a gram-negative bacterium that is naturally resistant to many antibiotics …
Crystal structures of multidrug efflux transporters from Burkholderia pseudomallei suggest details of transport mechanism
BpeB and BpeF are multidrug efflux transporters from Burkholderia pseudomallei that
enable multidrug resistance. Here, we report the crystal structures of BpeB and BpeF at 2.94 …
enable multidrug resistance. Here, we report the crystal structures of BpeB and BpeF at 2.94 …
Transcriptomic analysis of longitudinal Burkholderia pseudomallei infecting the cystic fibrosis lung
The melioidosis bacterium, Burkholderia pseudomallei, is increasingly being recognised as
a pathogen in patients with cystic fibrosis (CF). We have recently catalogued genome-wide …
a pathogen in patients with cystic fibrosis (CF). We have recently catalogued genome-wide …
Conservation of resistance-nodulation-cell division efflux pump-mediated antibiotic resistance in Burkholderia cepacia complex and Burkholderia pseudomallei …
Burkholderia cepacia complex (Bcc) and Burkholderia pseudomallei complex (Bpc) species
include pathogens that are typically multidrug resistant. Dominant intrinsic and acquired …
include pathogens that are typically multidrug resistant. Dominant intrinsic and acquired …
Taking the next-gen step: Comprehensive antimicrobial resistance detection from Burkholderia pseudomallei
Background Antimicrobial resistance (AMR) poses a major threat to human health. Whole-
genome sequencing holds great potential for AMR identification; however, there remain …
genome sequencing holds great potential for AMR identification; however, there remain …