A guide to the composition and functions of the extracellular matrix

NK Karamanos, AD Theocharis, Z Piperigkou… - The FEBS …, 2021 - Wiley Online Library
Extracellular matrix (ECM) is a dynamic 3‐dimensional network of macromolecules that
provides structural support for the cells and tissues. Accumulated knowledge clearly …

Gelatin as it is: history and modernity

OV Mikhailov - International journal of molecular sciences, 2023 - mdpi.com
The data concerning the synthesis and physicochemical characteristics of one of the
practically important proteins—gelatin, as well as the possibilities of its practical application …

The extracellular matrix in ischemic and nonischemic heart failure

NG Frangogiannis - Circulation research, 2019 - ahajournals.org
The ECM (extracellular matrix) network plays a crucial role in cardiac homeostasis, not only
by providing structural support, but also by facilitating force transmission, and by transducing …

[HTML][HTML] Hydrolyzed collagen—sources and applications

A León-López, A Morales-Peñaloza… - Molecules, 2019 - mdpi.com
Hydrolyzed collagen (HC) is a group of peptides with low molecular weight (3–6 KDa) that
can be obtained by enzymatic action in acid or alkaline media at a specific incubation …

Collagen-based formulations for wound healing: A literature review

S Sharma, VK Rai, RK Narang, TS Markandeywar - Life sciences, 2022 - Elsevier
Wounds have always been the point of concern owing to the involvement of infections and
the level of severity. Therefore, the management of wounds always requires additional effort …

Into the tissues: Extracellular matrix and its artificial substitutes: Cell signalling mechanisms

A Bandzerewicz, A Gadomska-Gajadhur - Cells, 2022 - mdpi.com
The existence of orderly structures, such as tissues and organs is made possible by cell
adhesion, ie, the process by which cells attach to neighbouring cells and a supporting …

[HTML][HTML] Collagen fibril formation in vitro: From origin to opportunities

DM Darvish - Materials Today Bio, 2022 - Elsevier
Sometimes, to move forward, it is necessary to look back. Collagen type I is one of the most
commonly used biomaterials in tissue engineering and regenerative medicine. There are a …

[HTML][HTML] Collagen remodeling along cancer progression providing a novel opportunity for cancer diagnosis and treatment

K Song, Z Yu, X Zu, G Li, Z Hu, Y Xue - International journal of molecular …, 2022 - mdpi.com
The extracellular matrix (ECM) is a significant factor in cancer progression. Collagens, as the
main component of the ECM, are greatly remodeled alongside cancer development. More …

Collagen-based tissue engineering strategies for vascular medicine

F Copes, N Pien, S Van Vlierberghe… - … in bioengineering and …, 2019 - frontiersin.org
Cardiovascular diseases (CVDs) account for the 31% of total death per year, making them
the first cause of death in the world. Atherosclerosis is at the root of the most life-threatening …

The fibrotic tumor stroma

M Yamauchi, TH Barker, DL Gibbons, JM Kurie - The Journal of clinical …, 2018 - jci.org
Intratumoral fibrosis results from the deposition of a cross-linked collagen matrix by cancer-
associated fibroblasts (CAFs). This type of fibrosis has been shown to exert mechanical …