Aconitine: A review of its pharmacokinetics, pharmacology, toxicology and detoxification
Y Gao, H Fan, A Nie, K Yang, H **ng, Z Gao… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Aconitine, a C 19-norditerpenoid alkaloid, derives from
many medicinal plants such as Aconitum carmichaelii Debx.(Chinese: 乌头), Aconitum …
many medicinal plants such as Aconitum carmichaelii Debx.(Chinese: 乌头), Aconitum …
Cardiac efficacy and toxicity of aconitine: A new frontier for the ancient poison
W Zhou, H Liu, LZ Qiu, LX Yue… - Medicinal research …, 2021 - Wiley Online Library
Aconitine (AC) is well‐known as the main toxic ingredient and active compound of Aconitum
species, of which several aconites are essential herbal medicines of Traditional Chinese …
species, of which several aconites are essential herbal medicines of Traditional Chinese …
Comprehensive insight into the pharmacology, pharmacokinetics, toxicity, detoxification and extraction of hypaconitine from Aconitum plants
G **ang, S Guo, J Qin, H Gao, Y Zhang… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Hypaconitine (HA), a diterpenoid alkaloid, mainly derived
from Aconitum plants such as Acoitum carmichaeli Debx. And Aconitum nagarum Stapf., has …
from Aconitum plants such as Acoitum carmichaeli Debx. And Aconitum nagarum Stapf., has …
Design, synthesis, and biological evaluation of low-toxic lappaconitine derivatives as potential analgesics
Y Li, Y Shang, X Li, Y Zhang, J **e, L Chen… - European Journal of …, 2022 - Elsevier
The C 18-diterpenoid alkaloid lappaconitine (LA) is a non-addictive analgesic used in
China. The toxicity (LD 50= 11.7 mg/kg) limits its application. Two series of LA derivatives …
China. The toxicity (LD 50= 11.7 mg/kg) limits its application. Two series of LA derivatives …
Natural Composition and Biosynthetic Pathways of Alkaloids in Medicinal Dendrobium Species
C Song, J Ma, G Li, H Pan, Y Zhu, Q **… - Frontiers in Plant …, 2022 - frontiersin.org
Dendrobium is the second biggest genus in the Orchidaceae family, some of which have
both ornamental and therapeutic values. Alkaloids are a group of active chemicals found in …
both ornamental and therapeutic values. Alkaloids are a group of active chemicals found in …
Pyrrolidine alkaloids and their promises in pharmacotherapy
This review aimed at summarizing the literature pertaining to the biological activities of
pyrrolidine alkaloids and their derivatives obtained from various sources. For this purpose …
pyrrolidine alkaloids and their derivatives obtained from various sources. For this purpose …
Non-alkaloidal constituents from the genus Aconitum: a review
T Yin, H Zhou, L Cai, Z Ding - RSC advances, 2019 - pubs.rsc.org
Species of the genus Aconitum are widely distributed in the north temperate region and
have been used in traditional medicine since antiquity due to their biological activities …
have been used in traditional medicine since antiquity due to their biological activities …
Cardiotoxicity evaluation and comparison of diterpene alkaloids on zebrafish
Q Ye, H Liu, C Fang, Y Liu, X Liu, J Liu… - Drug and Chemical …, 2021 - Taylor & Francis
Diterpene alkaloids (DAs) have a broad spectrum of pharmacological activities, but
exhibiting extremely serious cardiotoxicity to induce arrhythmia, heart arrest, even death …
exhibiting extremely serious cardiotoxicity to induce arrhythmia, heart arrest, even death …
Discrimination of the Geographical Origin of the Lateral Roots of Aconitum carmichaelii Using the Fingerprint, Multicomponent Quantification, and Chemometric …
LL Miao, QM Zhou, C Peng, CW Meng, XY Wang… - Molecules, 2019 - mdpi.com
Fuzi is a well-known traditional Chinese medicine developed from the lateral roots of
Aconitum carmichaelii Debx. It is rich in alkaloids that display a wide variety of bioactivities …
Aconitum carmichaelii Debx. It is rich in alkaloids that display a wide variety of bioactivities …
Benzoylaconine: Potential Therapeutic Agent for Cardiovascular Diseases From Fuzi
C Xu, L Tang, L Hu, Y Huang, J Tang… - Cardiovascular …, 2024 - Wiley Online Library
Modern pharmacological studies have elucidated the presence of aconitine (AC) alkaloids,
polysaccharides, and saponins as the primary bioactive constituents of Fuzi. Among these …
polysaccharides, and saponins as the primary bioactive constituents of Fuzi. Among these …