A brief review on solid lipid nanoparticles: Part and parcel of contemporary drug delivery systems

Y Duan, A Dhar, C Patel, M Khimani, S Neogi… - RSC …, 2020 - pubs.rsc.org
Drug delivery technology has a wide spectrum, which is continuously being upgraded at a
stupendous speed. Different fabricated nanoparticles and drugs possessing low solubility …

[HTML][HTML] Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers

S Haddadzadegan, F Dorkoosh… - Advanced drug delivery …, 2022 - Elsevier
The oral administration of therapeutic peptides and proteins is favoured from a patient and
commercial point of view. In order to reach the systemic circulation after oral administration …

Strategies to address low drug solubility in discovery and development

HD Williams, NL Trevaskis, SA Charman… - Pharmacological …, 2013 - Elsevier
Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …

Microemulsions and nanoemulsions in skin drug delivery

EB Souto, A Cano, C Martins-Gomes, TE Coutinho… - Bioengineering, 2022 - mdpi.com
Microemulsions and nanoemulsions are lipid-based pharmaceutical systems with a high
potential to increase the permeation of drugs through the skin. Although being isotropic …

Solid lipid nanoparticles and nanostructured lipid carriers as novel drug delivery systems: Applications, advantages and disadvantages

P Ghasemiyeh… - Research in …, 2018 - journals.lww.com
During the recent years, more attentions have been focused on lipid base drug delivery
system to overcome some limitations of conventional formulations. Among these delivery …

Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products

J Pardeike, A Hommoss, RH Müller - International journal of pharmaceutics, 2009 - Elsevier
Solid lipid nanoparticles (SLN) are distinguishable from nanostructured lipid carriers (NLC)
by the composition of the solid particle matrix. Both are an alternative carrier system to …

[HTML][HTML] Nanostructured lipid carriers for site-specific drug delivery

A Khosa, S Reddi, RN Saha - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Nanostructured lipid carriers (NLC), comprises of a blend of solid and liquid lipids which
results in a partially crystallized lipid system and imparts many advantages over solid lipid …

Preparation of solid lipid nanoparticles and nanostructured lipid carriers for drug delivery and the effects of preparation parameters of solvent injection method

VA Duong, TTL Nguyen, HJ Maeng - Molecules, 2020 - mdpi.com
Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) have emerged as
potential drug delivery systems for various applications that are produced from …

Lipid nanoparticles: Different preparation techniques, characterization, hurdles, and strategies for the production of solid lipid nanoparticles and nanostructured lipid …

P Ganesan, D Narayanasamy - Sustainable Chemistry and Pharmacy, 2017 - Elsevier
The bioavailability of an orally administered drug primarily depends on its solubility in the
GIT and its permeability across cell membranes. Also, a drug in solution form is preferred for …

Recent advances in lipid nanoparticle formulations with solid matrix for oral drug delivery

S Das, A Chaudhury - Aaps Pharmscitech, 2011 - Springer
Lipid nanoparticles based on solid matrix have emerged as potential drug carriers to
improve gastrointestinal (GI) absorption and oral bioavailability of several drugs, especially …