Certain clinical features of schizophrenia, such as working memory disturbances, appear to
emerge from altered gamma oscillatory activity in the prefrontal cortex (PFC). Given the …

The kainic acid model of temporal lobe epilepsy has greatly contributed to the
understanding of the molecular, cellular and pharmacological mechanisms underlying …

Theta oscillations represent the" on-line" state of the hippocampus. The extracellular
currents underlying theta waves are generated mainly by the entorhinal input, CA3 …

Community-based studies suggest that cannabis products that are high in Δ9-
tetrahydrocannabinol (THC) but low in cannabidiol (CBD) are particularly hazardous for …

The discovery of cannabinoid receptors and subsequent identification of their endogenous
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …

Gamma frequency oscillations are thought to provide a temporal structure for information
processing in the brain. They contribute to cognitive functions, such as memory formation …

The endocannabinoids are a family of lipid messengers that engage the cell surface
receptors that are targeted by Δ9-tetrahydrocannabinol, the active principle in marijuana …

Recent advances in the understanding of brain cannabinoid receptor function have renewed
interest in the association between cannabinoid compounds and psychosis. In a 3-day …

The endogenous cannabinoids (endocannabinoids) are lipid molecules that may mediate
retrograde signaling at central synapses and other forms of short-range neuronal …

Marijuana affects brain function primarily by activating the G-protein-coupled cannabinoid
receptor-1 (CB1),,, which is expressed throughout the brain at high levels. Two endogenous …