Current opinions on large cellular models.

M Hao, L Wei, F Yang, J Yao… - Quantitative …, 2024 - search.ebscohost.com
This document is an interview with leading researchers in the field of AI and biology,
discussing the development and applications of Large Cellular Models (LCMs) in biological …

ProteoMixture: A cell type deconvolution tool for bulk tissue proteomic data

P Teng, JP Schaaf, T Abulez, BL Hood, KN Wilson… - Iscience, 2024 - cell.com
Numerous multi-omic investigations of cancer tissue have documented varying and poor
pairwise transcript: protein quantitative correlations, and most deconvolution tools aiming to …

Multimodal joint deconvolution and integrative signature selection in proteomics

Y Pan, X Wang, J Sun, C Liu, J Peng, Q Li - Communications Biology, 2024 - nature.com
Deconvolution is an efficient approach for detecting cell-type-specific (cs) transcriptomic
signals without cellular segmentation. However, this type of methods may require a …

[HTML][HTML] Deep learning and machine learning applications in biomedicine

P Yan, Y Liu, Y Jia, T Zhao - Applied Sciences, 2023 - mdpi.com
The rise of omics research, spanning genomics, transcriptomics, proteomics, and
epigenomics, has revolutionized our understanding of biological systems. While the …

Generative Adversarial Networks for Heterogeneous Unsupervised Domain Adaptation Detection

HSM Mahalegi, A Farhadi, G Molnár… - 2024 IEEE 28th …, 2024 - ieeexplore.ieee.org
Domain adaptation, a subset of transfer learning, involves generating examples from two
related but differently distributed source and target domains. This paper introduces an …

High-resolution digital dissociation of brain tumors with deep multimodal autoencoder

J Sun, Y Pan, T Lin, K Smith, A Onar-Thomas… - bioRxiv, 2025 - biorxiv.org
Single-cell technologies enable high-resolution, multi-dimensional analysis of molecular
profiles in cancer biology but face challenges related to low coverage and cell annotation …

Genetic deconvolution of embryonic and maternal cell-free DNA in spent culture medium of human preimplantation embryos through deep learning

Z Zhang, J Qiao, Y Chen, P Zhou - bioRxiv, 2025 - biorxiv.org
Noninvasive preimplantation genetic testing for aneuploidy based on embryonic cell-free
DNA (cfDNA) released in spent embryo culture media (SECM) has brought hope in selecting …

Masked adversarial neural network for cell type deconvolution in spatial transcriptomics

L Huang, X Liu, S Wang, W Min - 2024 IEEE International …, 2024 - ieeexplore.ieee.org
Accurately determining cell type composition in disease-relevant tissues is crucial for
identifying disease targets. Most existing spatial transcriptomics (ST) technologies cannot …

Enhancing UAV Autonomous Navigation in Indoor Environments Using Reinforcement Learning and Convolutional Neural Networks

HSM Mahalegi, A Farhadi, G Molnár… - 2024 IEEE 22nd …, 2024 - ieeexplore.ieee.org
In recent years, the number of unmanned aerial vehicle (UAV) applications has increased.
However, navigating them indoors is still tricky because no GPS signals are available, and …

Chioso: Segmentation-free Annotation of Spatial Transcriptomics Data at Sub-cellular Resolution via Adversarial Learning

J Yu - bioRxiv, 2024 - biorxiv.org
Recent advances in spatial transcriptomics technology have produced full-transcriptomic
scale dataset with subcellular spatial resolutions. Here we present a new computational …