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[HTML][HTML] Blood-based biomarkers of cerebral small vessel disease
Age-associated cerebral small vessel disease (CSVD) represents a clinically heterogenous
condition, arising from diverse microvascular mechanisms. These lead to chronic …
condition, arising from diverse microvascular mechanisms. These lead to chronic …
Brain vascular health in ALS is mediated through motor cortex microvascular integrity
Brain vascular health appears to be critical for preventing the development of amyotrophic
lateral sclerosis (ALS) and slowing its progression. ALS patients often demonstrate …
lateral sclerosis (ALS) and slowing its progression. ALS patients often demonstrate …
Deep learning for 3D vascular segmentation in hierarchical phase contrast tomography: a case study on kidney
Automated blood vessel segmentation is critical for biomedical image analysis, as vessel
morphology changes are associated with numerous pathologies. Still, precise segmentation …
morphology changes are associated with numerous pathologies. Still, precise segmentation …
Self-supervised learning for accurately modelling hierarchical evolutionary patterns of cerebrovasculature
Cerebrovascular abnormalities are critical indicators of stroke and neurodegenerative
diseases like Alzheimer's disease (AD). Understanding the normal evolution of brain vessels …
diseases like Alzheimer's disease (AD). Understanding the normal evolution of brain vessels …
Computational modeling of multiscale collateral blood supply in a whole-brain-scale arterial network
The cerebral arterial network covering the brain cortex has multiscale anastomosis
structures with sparse intermediate anastomoses (O [102] μm in diameter) and dense pial …
structures with sparse intermediate anastomoses (O [102] μm in diameter) and dense pial …
Insights into hippocampal perfusion using high-resolution, multi-modal 7T MRI
We present a comprehensive study on the non-invasive measurement of hippocampal
perfusion. Using high-resolution 7 tesla arterial spin labeling (ASL) data, we generated …
perfusion. Using high-resolution 7 tesla arterial spin labeling (ASL) data, we generated …
Germany's journey toward 14 Tesla human magnetic resonance
Multiple sites within Germany operate human MRI systems with magnetic fields either at 7
Tesla or 9.4 Tesla. In 2013, these sites formed a network to facilitate and harmonize the …
Tesla or 9.4 Tesla. In 2013, these sites formed a network to facilitate and harmonize the …
Review of in silico models of cerebral blood flow in health and pathology
In this review, we provide a summary of the state-of-the-art in the in silico modelling of
cerebral blood flow (CBF) and its application in in silico clinical trials. CBF plays a key role in …
cerebral blood flow (CBF) and its application in in silico clinical trials. CBF plays a key role in …
Flow reduction due to arterial catheterization during stroke treatment–A computational study using a distributed compartment model
The effectiveness of various stroke treatments depends on the anatomical variability of the
cerebral vasculature, particularly the collateral blood vessel network. Collaterals at the level …
cerebral vasculature, particularly the collateral blood vessel network. Collaterals at the level …
Modeling venous bias in resting state functional MRI metrics
Resting‐state (rs) functional magnetic resonance imaging (fMRI) is used to detect low‐
frequency fluctuations in the blood oxygen‐level dependent (BOLD) signal across brain …
frequency fluctuations in the blood oxygen‐level dependent (BOLD) signal across brain …