[HTML][HTML] Blood-based biomarkers of cerebral small vessel disease

LY Wu, YL Chai, IK Cheah, RSL Chia, S Hilal… - Ageing research …, 2024 - Elsevier
Age-associated cerebral small vessel disease (CSVD) represents a clinically heterogenous
condition, arising from diverse microvascular mechanisms. These lead to chronic …

Brain vascular health in ALS is mediated through motor cortex microvascular integrity

S Schreiber, J Bernal, P Arndt, F Schreiber, P Müller… - Cells, 2023 - mdpi.com
Brain vascular health appears to be critical for preventing the development of amyotrophic
lateral sclerosis (ALS) and slowing its progression. ALS patients often demonstrate …

Deep learning for 3D vascular segmentation in hierarchical phase contrast tomography: a case study on kidney

E Yagis, S Aslani, Y Jain, Y Zhou, S Rahmani… - Scientific Reports, 2024 - nature.com
Automated blood vessel segmentation is critical for biomedical image analysis, as vessel
morphology changes are associated with numerous pathologies. Still, precise segmentation …

Self-supervised learning for accurately modelling hierarchical evolutionary patterns of cerebrovasculature

B Guo, Y Chen, J Lin, B Huang, X Bai, C Guo… - Nature …, 2024 - nature.com
Cerebrovascular abnormalities are critical indicators of stroke and neurodegenerative
diseases like Alzheimer's disease (AD). Understanding the normal evolution of brain vessels …

Computational modeling of multiscale collateral blood supply in a whole-brain-scale arterial network

T Otani, N Nishimura, H Yamashita, S Ii… - PLOS Computational …, 2023 - journals.plos.org
The cerebral arterial network covering the brain cortex has multiscale anastomosis
structures with sparse intermediate anastomoses (O [102] μm in diameter) and dense pial …

Insights into hippocampal perfusion using high-resolution, multi-modal 7T MRI

RAM Haast, S Kashyap, D Ivanov, MD Yousif… - Proceedings of the …, 2024 - pnas.org
We present a comprehensive study on the non-invasive measurement of hippocampal
perfusion. Using high-resolution 7 tesla arterial spin labeling (ASL) data, we generated …

Germany's journey toward 14 Tesla human magnetic resonance

ME Ladd, HH Quick, O Speck, M Bock… - … resonance materials in …, 2023 - Springer
Multiple sites within Germany operate human MRI systems with magnetic fields either at 7
Tesla or 9.4 Tesla. In 2013, these sites formed a network to facilitate and harmonize the …

Review of in silico models of cerebral blood flow in health and pathology

S Payne, TI Józsa, WK El-Bouri - Progress in Biomedical …, 2023 - iopscience.iop.org
In this review, we provide a summary of the state-of-the-art in the in silico modelling of
cerebral blood flow (CBF) and its application in in silico clinical trials. CBF plays a key role in …

Flow reduction due to arterial catheterization during stroke treatment–A computational study using a distributed compartment model

A Pradhan, F Mut, M Sosale… - International Journal for …, 2024 - Wiley Online Library
The effectiveness of various stroke treatments depends on the anatomical variability of the
cerebral vasculature, particularly the collateral blood vessel network. Collaterals at the level …

Modeling venous bias in resting state functional MRI metrics

J Huck, AT Jäger, U Schneider, S Grahl… - Human Brain …, 2023 - Wiley Online Library
Resting‐state (rs) functional magnetic resonance imaging (fMRI) is used to detect low‐
frequency fluctuations in the blood oxygen‐level dependent (BOLD) signal across brain …