Eugenol: A novel therapeutic agent for the inhibition of Candida species infection

M Didehdar, Z Chegini, A Shariati - Frontiers in Pharmacology, 2022 - frontiersin.org
The high occurrence and mortality rates related to candidiasis emphasize the urgent need to
introduce new therapeutic approaches to treat this infection. Eugenol, the main phenolic …

Natural Compounds: A Hopeful Promise as an Antibiofilm Agent Against Candida Species

A Shariati, M Didehdar, S Razavi, M Heidary… - Frontiers in …, 2022 - frontiersin.org
The biofilm communities of Candida are resistant to various antifungal treatments. The ability
of Candida to form biofilms on abiotic and biotic surfaces is considered one of the most …

Clove Essential Oil and Its Main Constituent, Eugenol, as Potential Natural Antifungals against Candida spp. Alone or in Combination with Other Antimycotics Due to …

A Biernasiuk, T Baj, A Malm - Molecules, 2022 - mdpi.com
The occurrence of candidiasis, including superficial infections, has recently increased
dramatically, especially in immunocompromised patients. Their treatment is often ineffective …

[HTML][HTML] Out of control: the need for standardised solvent approaches and data reporting in antibiofilm assays incorporating dimethyl-sulfoxide (DMSO)

K Summer, J Browne, M Hollanders, K Benkendorff - Biofilm, 2022 - Elsevier
Bacteria in biofilm formations are up to 1000 times less susceptible to antibiotics than their
planktonic counterparts. Recognition of the role of biofilms in∼ 80% of chronic infections …

Candida albicans Reactive Oxygen Species (ROS)-Dependent Lethality and ROS-Independent Hyphal and Biofilm Inhibition by Eugenol and Citral

Z Shahina, E Ndlovu, O Persaud, T Sultana… - Microbiology …, 2022 - journals.asm.org
Candida albicans is part of the normal human flora but is most frequently isolated as the
causative opportunistic pathogen of candidiasis. Plant-based essential oils and their …

[HTML][HTML] Antifungal Activity of Natural Compounds vs. Candida spp.: A Mixture of Cinnamaldehyde and Eugenol Shows Promising In Vitro Results

IM Saracino, C Foschi, M Pavoni, R Spigarelli… - Antibiotics, 2022 - mdpi.com
Candida spp. are commensal organisms of the skin, mucous membranes, gastrointestinal
tract, blood, and vagina of animals and humans. In recent decades, the incidence of human …

Mixed biofilms of pathogenic Candida-bacteria: regulation mechanisms and treatment strategies

F Khan, NI Bamunuarachchi, DTN Pham… - Critical reviews in …, 2021 - Taylor & Francis
Mixed-species biofilm is one of the most frequently recorded clinical problems. Mixed
biofilms develop as a result of interactions between microorganisms of a single or multiple …

Pharmacodynamic, pharmacokinetic, toxicity, and recent advances in Eugenol's potential benefits against natural and chemical noxious agents: A mechanistic review

N Tavvabi-Kashani, M Hasanpour, VB Rahimi… - Toxicon, 2024 - Elsevier
The active biological phytochemicals, crucial compounds employed in creating hundreds of
medications, are derived from valuable and medicinally significant plants. These …

Mannosylated Systems for Targeted Delivery of Antibacterial Drugs to Activated Macrophages

ID Zlotnikov, MA Vigovskiy, MP Davydova… - International Journal of …, 2022 - mdpi.com
Macrophages are a promising target for drug delivery to influence macrophage-associated
processes in the body, namely due to the presence of resistant microorganisms in …

[HTML][HTML] Cinnamon Leaf and Clove Essential Oils Are Potent Inhibitors of Candida albicans Virulence Traits

Z Shahina, A Molaeitabari, T Sultana, TES Dahms - Microorganisms, 2022 - mdpi.com
Plant-based essential oils are promising anti-virulence agents against the multidrug-
resistant opportunistic pathogen Candida albicans. Gas chromatography–mass …