In recent years, the formulation of some immunoassays with high-sensitivity analytical
performance allowed the accurate measurement of cardiac troponin I (cTnI) and T (cTnT) …

The high-sensitivity immunoassays for cardiac troponin I (hs-cTnI) and cardiac troponin T (hs-
cTnT) are recommended by all the most recent international guidelines as gold standard …

In accordance with all the most recent international guidelines, the variation of circulating
levels of cardiac troponins I and T, measured with high-sensitivity methods (hs-cTnI and hs …

Modern laboratory methods for determining biomarkers of cardiovascular diseases are
highly sensitive and can detect almost single molecules in human biological fluids …

Circulating biomarkers and imaging techniques provide independent and complementary
information to guide management of heart failure (HF). This consensus document by the …

Objectives The neurofilament light chain (NfL) has emerged as a versatile biomarker for
CNS-diseases and is approaching clinical use. The observed changes in NfL levels are …

Abstract The 4th Universal Definition of Myocardial Infarction has stimulated considerable
debate since its publication in 2018. The intention was to define the types of myocardial …

Summary Background Circadian (24-h) rhythms are important regulators in physiology and
disease, but systemic disease may disrupt circadian rhythmicity. Heart failure (HF) is a …

Background The availability of high-sensitivity cTnI (hs-cTnI) assays has improved the
accuracy of cTn measurements at concentrations around and below the 99th percentile …

The definition of a high-sensitivity cardiac Troponin (cTn) assay describes the ability to
quantify a cardiac biomarker level in at least 50% of healthy individuals. This advance in …