Variants of UNC13A, a critical gene for synapse function, increase the risk of amyotrophic
lateral sclerosis and frontotemporal dementia,–, two related neurodegenerative diseases …

Oncogenic RAS signaling reprograms gene expression through both transcriptional and
post‐transcriptional mechanisms. While transcriptional regulation downstream of RAS is …

Abstract Tudor Interacting Repair Regulator (TIRR) is an RNA-binding protein (RBP) that
interacts directly with 53BP1, restricting its access to DNA double-strand breaks (DSBs) and …

Abstract N6-methyladenosine (m6A) RNA modification impacts mRNA fate primarily via
reader proteins, which dictate processes in development, stress, and disease. Yet little is …

An intronic GGGGCC repeat expansion in C9orf72 is a common genetic cause of
amyotrophic lateral sclerosis and frontotemporal dementia. The repeats are transcribed in …

Signaling pathways drive cell fate transitions largely by changing gene expression.
However, the mechanisms for rapid and selective transcriptome rewiring in response to …

It is currently not known whether mRNAs fulfill structural roles in the cytoplasm. Here, we
report the fragile X-related protein 1 (FXR1) network, an mRNA-protein (mRNP) network …

Our expanding knowledge of the roles small regulatory RNAs play across numerous areas
of biology, coupled with the promise of RNA-targeted therapies and small RNA-based …

Characterising RNA–protein interaction dynamics is fundamental to understand how
bacteria respond to their environment. In this study, we have analysed the dynamics of 91 …

CLIP technologies are now widely used to study RNA–protein interactions and many data
sets are now publicly available. An important first step in CLIP data exploration is the visual …