Biospecimens acquired during routine medical practice are the primary sources of molecular
information about patients and their diseases that underlies precision medicine and …

The concept of personalized medicine is predominantly been pursued through genomic and
transcriptomic technologies, leading to the identification of multiple mutations in a large …

Traditional histochemical staining of post-mortem samples often confronts inferior staining
quality due to autolysis caused by delayed fixation of cadaver tissue, and such chemical …

Simple Summary The rapid development of technology has enabled numerous applications
of artificial intelligence (AI), especially in medical science. Histopathological assessment of …

The loss of antigenicity in archival formalin-fixed paraffin-embedded (FFPE) tissue sections
negatively affects both diagnostic histopathology and advanced molecular studies. The …

Dr. Lester's Manual of Surgical Pathology, 3rd Edition offers complete, practical guidance on
the evaluation of the surgical pathology specimen, from its arrival in the department to …

Determining the presence of MYC gene rearrangements is becoming an increasingly
important part of the diagnostic workup in aggressive lymphoma. Cytogenetic MYC …

Paraffin embedding is a standard technique used in clinical and research laboratories to
create a formalin-fixed, paraffin-embedded (FFPE) block of tissue. Formalin-fixed tissue …

Traditional approaches to sequence analysis are widely used to guide therapy for patients
with lung and colorectal cancer and for patients with melanoma, sarcomas (eg …

Preanalytical handling of tissue samples can influence bioanalyte quality and ultimately
outcome of analytical results. The aim of this study was to compare RNA quality …