The stiffness of living tissues and its implications for tissue engineering

CF Guimarães, L Gasperini, AP Marques… - Nature Reviews …, 2020 - nature.com
The past 20 years have witnessed ever-growing evidence that the mechanical properties of
biological tissues, from nanoscale to macroscale dimensions, are fundamental for cellular …

Microglia priming with aging and stress

A Niraula, JF Sheridan, JP Godbout - Neuropsychopharmacology, 2017 - nature.com
The population of aged individuals is increasing worldwide and this has significant health
and socio-economic implications. Clinical and experimental studies on aging have …

Multi-material digital light processing bioprinting of hydrogel-based microfluidic chips

A Bhusal, E Dogan, HA Nguyen, O Labutina… - …, 2021 - iopscience.iop.org
Recent advancements in digital-light-processing (DLP)-based bioprinting and hydrogel
engineering have enabled novel developments in organs-on-chips. In this work, we …

Magnetic resonance elastography (MRE) of the human brain: technique, findings and clinical applications

LV Hiscox, CL Johnson, E Barnhill… - Physics in Medicine …, 2016 - iopscience.iop.org
Neurological disorders are one of the most important public health concerns in developed
countries. Established brain imaging techniques such as magnetic resonance imaging (MRI) …

Brain stiffness increases with myelin content

J Weickenmeier, R de Rooij, S Budday, P Steinmann… - Acta biomaterialia, 2016 - Elsevier
Brain stiffness plays an important role in neuronal development and disease, but reported
stiffness values vary significantly for different species, for different brains, and even for …

MR elastography of the brain and its application in neurological diseases

MC Murphy, J Huston III, RL Ehman - Neuroimage, 2019 - Elsevier
Magnetic resonance elastography (MRE) is an imaging technique for noninvasively and
quantitatively assessing tissue stiffness, akin to palpation. MRE is further able assess the …

[HTML][HTML] Regional brain stiffness changes across the Alzheimer's disease spectrum

MC Murphy, DT Jones, CR Jack Jr, KJ Glaser… - NeuroImage: Clinical, 2016 - Elsevier
Magnetic resonance elastography (MRE) is an MRI-based technique to noninvasively
measure tissue stiffness. Currently well established for clinical use in the liver, MRE is …

Mechanobiology of the brain in ageing and Alzheimer's disease

CM Hall, E Moeendarbary… - European Journal of …, 2021 - Wiley Online Library
Just as the epigenome, the proteome and the electrophysiological properties of a cell
influence its function, so too do its intrinsic mechanical properties and its extrinsic …

[HTML][HTML] Aging brain mechanics: Progress and promise of magnetic resonance elastography

LV Hiscox, H Schwarb, MDJ McGarry, CL Johnson - Neuroimage, 2021 - Elsevier
Novel neuroimaging techniques that can sensitivity characterize healthy brain aging and
detect subtle neuropathologies have enormous potential to assist in the early detection of …

[KIRJA][B] Magnetic resonance elastography: physical background and medical applications

S Hirsch, J Braun, I Sack - 2017 - books.google.com
Magnetic resonance elastography (MRE) is a medical imaging technique that combines
magnetic resonance imaging (MRI) with mechanical vibrations to generate maps of …