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Targeted drug delivery to the brain via intranasal nanoemulsion: Available proof of concept and existing challenges
Intranasal delivery has shown to circumvent blood-brain-barrier (BBB) and deliver the drugs
into the CNS at a higher rate and extent than other conventional routes. The mechanism of …
into the CNS at a higher rate and extent than other conventional routes. The mechanism of …
Nanotechnology-based drug delivery systems for Alzheimer's disease management: Technical, industrial, and clinical challenges
Alzheimer's disease (AD) is a neurodegenerative disease with high prevalence in the
rapidly growing elderly population in the develo** world. The currently FDA approved …
rapidly growing elderly population in the develo** world. The currently FDA approved …
Nano-carrier enabled drug delivery systems for nose to brain targeting for the treatment of neurodegenerative disorders
A major hurdle for the treatment of neurodegenerative disorders is the inability of drug
molecules to cross the blood-brain barrier (BBB). Many anti-Parkinson and anti-Alzheimer …
molecules to cross the blood-brain barrier (BBB). Many anti-Parkinson and anti-Alzheimer …
Utilization of propranolol hydrochloride mucoadhesive invasomes as a locally acting contraceptive: in-vitro, ex-vivo, and in-vivo evaluation
It was found that propranolol hydrochloride (PNL), which is a beta-blocker used for
hypertension treatment, has a potent spermicidal activity through local anesthetic activity or …
hypertension treatment, has a potent spermicidal activity through local anesthetic activity or …
[HTML][HTML] Recent insights into therapeutic potential and nanostructured carrier systems of Centella asiatica: An evidence-based review
ABSTRACT Introduction: Centella asiatica (L.) Urb. is an authentic herbal medicine that is
frequently used in Southeast Asian regions and scientific investigations have demonstrated …
frequently used in Southeast Asian regions and scientific investigations have demonstrated …
Formulation and evaluation of simvastatin cubosomal nanoparticles for assessing its wound healing effect
Wound healing is one of the most challenging medical circumstances for patients.
Pathogens can infect wounds, resulting in tissue damage, inflammation, and disruption of …
Pathogens can infect wounds, resulting in tissue damage, inflammation, and disruption of …
Intranasal nanoparticulate systems as alternative route of drug delivery
There is always a need for alternative and efficient methods of drug delivery. The nasal
cavity can be considered as a non-invasive and efficient route of administration. It has been …
cavity can be considered as a non-invasive and efficient route of administration. It has been …
Nanoemulsions: summary of a decade of research and recent advances
Nanoemulsions consist of a combination of several components such as oil, water,
emulsifiers, surfactants and cosurfactants. Various techniques for producing nanoemulsions …
emulsifiers, surfactants and cosurfactants. Various techniques for producing nanoemulsions …
[HTML][HTML] Synthesis and characterization of chitosan-decorated nanoemulsion gel of 5-fluorouracil for topical delivery
(1) Background: The present study aimed to prepare chitosan-coated nanoemulsion gel
containing 5-fluorouracil for enhanced topical delivery.(2) Methods: To formulate the …
containing 5-fluorouracil for enhanced topical delivery.(2) Methods: To formulate the …
Olive oil based methotrexate loaded topical nanoemulsion gel for the treatment of imiquimod induced psoriasis-like skin inflammation in an animal model
Simple Summary Psoriasis, being chronic inflammatory illness, provoked by genetic and
environmental factors is linked to several other life-threatening diseases. Methotrexate is …
environmental factors is linked to several other life-threatening diseases. Methotrexate is …