Application of SERS-based nanobiosensors to metabolite biomarkers of CKD

D Kukkar, M Chhillar, KH Kim - Biosensors and Bioelectronics, 2023 - Elsevier
A clinical diagnosis of chronic kidney disease (CKD) is commonly achieved by estimating
the serum levels of urea and creatinine (CR). Given the limitations of the conventional …

Surface-enhanced Raman spectroscopy as a powerful method for the analysis of Chinese herbal medicines

CX Xu, P Song, Z Yu, YH Wang - Analyst, 2024 - pubs.rsc.org
Chinese herbal medicines (CHMs) derived from nature have received increasing attention
and become more popular. Due to their diverse production processes, complex ingredients …

Handheld microfluidic multiple detection device for concurrent blood urea nitrogen and creatinine ratio determination using colorimetric approach

CH Ko, CC Tseng, SY Lu, CC Lee, S Kim… - Sensors and Actuators B …, 2025 - Elsevier
A novel microfluidic multiple detection (MMD) platform consisting of a microfluidic chip and a
self-built detection system is proposed for determining the creatinine (CRE) and blood urea …

“Partner” cellulose gel with “dialysis” function: Achieve the integration of filtration-enrichment-SERS detection

H Wang, P Xu, Y Chen, C Wang, S Chen, J Ren… - Biosensors and …, 2025 - Elsevier
Hydrogel and aerogel materials have garnered significant attention in constructing effective
surface-enhanced Raman spectroscopy (SERS) substrates due to their excellent adsorption …

Ag nanoparticle-embedded fish scales as SERS substrates for sensitive detection of forever chemical in real samples

J Kumar, A **achandran, VK Ponnusamy… - Applied Surface …, 2024 - Elsevier
Biological materials with unique surface properties provide a new avenue for fabricating
green and sensitive SERS-active substrates. Herein, we present a simple but efficient …

Diaper-based wearable SERS sensing system with a silver nano dual-structure composite hydrogel for the detection of biomarkers and pH in urine

R Liu, Q Nie, Y Wang, Y Wu, Y Tu, C **e, X **ao… - Chemical Engineering …, 2024 - Elsevier
Wearable sensors are essential for continuous monitoring of an individual's health status to
enable personalized health management. Urine as a typical non-invasive biological fluid is …

Coaxial electrospinning of Au@ silicate/poly (vinyl alcohol) core/shell composite nanofibers with non-covalently immobilized gold nanoparticles for preparing flexible …

YF Chen, YC Lee, JCM Lee, JW Li, CW Chiu - Advanced Composites and …, 2024 - Springer
As substrates for surface-enhanced Raman spectroscopy (SERS), novel core/shell
composite nanofiber films were prepared by coaxial electrospinning. The shell comprised …

Au/SiNCA-based SERS analysis coupled with machine learning for the early-stage diagnosis of cisplatin-induced liver injury

S Ge, G Chen, D Cao, H Lin, Z Liu, M Yu, S Wang… - Analytica Chimica …, 2023 - Elsevier
Cisplatin has been widely applied in the clinical treatment of various cancers, whereas liver
injury induced by its hepatotoxicity is still a severe issue. Reliable identification of early …

SERS calibration substrate with a silent region internal standard for reliable simultaneous detection of multiple antibiotics in water

ZH Chen, N Sun, JP Li, JW Zheng, YH Wang, XS Zhou… - Talanta, 2025 - Elsevier
As the extensive use of antibiotics has led to the rapid spread of antibiotic resistance, there
is an urgent need for quantitative assessment of antibiotic residues in the environment …

The potential applications of raman spectroscopy in kidney diseases

C Delrue, MM Speeckaert - Journal of Personalized Medicine, 2022 - mdpi.com
Raman spectroscopy (RS) is a spectroscopic technique based on the inelastic interaction of
incident electromagnetic radiation (from a laser beam) with a polarizable molecule, which …