The SPOT-synthesis technique: synthetic peptide arrays on membrane supports—principles and applications

R Frank - Journal of immunological methods, 2002 - Elsevier
Presented first in 1990 at the 21st European Peptide Symposium in Barcelona, Spain [Frank,
R., Güler, S., Krause, S., Lindenmaier, W., 1991. Facile and rapid 'spot synthesis' of large …

Antigenic structures of proteins: their determination has revealed important aspects of immune recognition and generated strategies for synthetic mimicking of protein …

MZ Atassi - European journal of biochemistry, 1984 - Wiley Online Library
Studies in this laboratory have resulted in the delineation and synthetic verification of
several complete protein antigenic structures that are recognized by antibodies. More …

Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acid.

HM Geysen, RH Meloen… - Proceedings of the …, 1984 - National Acad Sciences
A procedure is described for rapid concurrent synthesis on solid supports of hundreds of
peptides, of sufficient purity to react in an enzyme-linked immunosorbent assay. Interaction …

Human autoantibodies reactive with synthetic autoantigens from T-cell receptor beta chain.

JJ Marchalonis, H Kaymaz… - Proceedings of the …, 1992 - National Acad Sciences
We used map** with synthetic overlap** peptides in combination with molecular
modeling to analyze the IgG antibodies that humans naturally produce against human T-cell …

Basic immunological aspects of botulinum toxin therapy

MZ Atassi - Movement disorders: official journal of the …, 2004 - Wiley Online Library
Previous studies in this laboratory had mapped the immune recognition profile of the regions
recognized antibodies (Abs) and by T cells on the protective HC domain (C‐terminal …

Map** of the regions on the heavy chain of botulinum neurotoxin A (BoNT/A) recognized by antibodies of cervical dystonia patients with immunoresistance to BoNT …

BZ Dolimbek, KR Aoki, LE Steward, J Jankovic… - Molecular …, 2007 - Elsevier
The purpose of this work was to map the entire recognition profile of the H chain of
botulinum neurotoxin A (BoNT/A) by Abs in sera that have protective anti-BoNT/A Abs by the …

Immunological detection of hemoglobin in bones of ancient Roman times and of Iron and Eneolithic Ages.

A Ascenzi, M Brunori, G Citro… - Proceedings of the …, 1985 - National Acad Sciences
Using an immunological method (immunoblot), we have established that hemoglobin (or
hemoglobin fragments) can be quantitatively determined in old and ancient bones, some of …

Exquisite specificity and peptide epitope recognition promiscuity, properties shared by antibodies from sharks to humans

JJ Marchalonis, MK Adelman, IF Robey… - Journal of Molecular …, 2001 - Wiley Online Library
This review considers definitions of the specificity of antibodies including the development of
recent concepts of recognition polyspecificity and epitope promiscuity. Using sets of …

Hypersensitivity to chironomids (non-biting midges): localization of the antigenic determinants within certain polypeptide sequences of hemoglobins (erythrocruorins) …

X Baur, M Dewair, G Fruhmann, H Aschauer… - Journal of Allergy and …, 1982 - Elsevier
Ninety-nine individuals who were in contact with larvae of chironomids were investigated.
Forty-three developed respiratory, conjunctival, or cutaneous hypersensitivity reactions upon …

Method of determining antigenically active amino acid sequences

HM Geysen - US Patent 5,595,915, 1997 - Google Patents
A method of detecting or determining a sequence of amino acids which is antigenically
active within a known amino acid sequence of a protein or portion thereof comprises the …