Metabolic magnetic resonance imaging (MRI) using hyperpolarized (HP) pyruvate is
becoming a non‐invasive technique for diagnosing, staging, and monitoring response to …

Signal amplification by reversible exchange (SABRE) is a rapidly develo** nuclear
magnetic resonance (NMR) hyperpolarization technique utilizing parahydrogen for dramatic …

We present an integrated, open-source device for parahydrogen-based hyperpolarization
processes in the microtesla field regime with a cost of components of less than $7000. The …

Hyperpolarization has become a powerful tool to enhance the sensitivity of magnetic
resonance. A universal tool to hyperpolarize small molecules in solution, however, has not …

Over the last two decades, hyperpolarized 13 C MRI has gained significance in both
preclinical and clinical studies, hereby relying on technologies like PHIP-SAH …

Real‐time visualization of metabolic processes in vivo provides crucial insights into
conditions like cancer and metabolic disorders. Metabolic magnetic resonance imaging …

Hyperpolarization of small peptides by parahydrogen-induced polarization (PHIP) to
increase the sensitivity of nuclear magnetic resonance (NMR) techniques is well …

Hyperpolarized [1-13C] pyruvate is the leading hyperpolarized injectable contrast agent and
is currently under evaluation in clinical trials for molecular imaging of metabolic diseases …

Nuclear spin hyperpolarization is a quantum effect that enhances the nuclear magnetic
resonance signal by several orders of magnitude and has enabled real-time metabolic …

Metronidazole is a prospective hyperpolarized MRI contrast agent with potential hypoxia
sensing utility for applications in cancer, stroke, neurodegenerative diseases, etc. We …