Patient centric pharmaceutical drug product design—The impact on medication adherence

E Menditto, V Orlando, G De Rosa, P Minghetti… - Pharmaceutics, 2020‏ - mdpi.com
Medication adherence is a growing concern for public health and poor adherence to therapy
has been associated with poor health outcomes and higher costs for patients. Interventions …

Patient-centric design of topical dermatological medicines

R Oliveira, IF Almeida - Pharmaceuticals, 2023‏ - mdpi.com
Topical treatments are essential approaches to skin diseases but are associated with poor
adherence. Topical vehicles have the primary purpose of ensuring drug effectiveness (by …

[HTML][HTML] Does the vehicle matter? Real-world evidence on adherence to topical treatment in psoriasis

A Teixeira, M Teixeira, V Almeida, R Gaio, T Torres… - Pharmaceutics, 2021‏ - mdpi.com
The influence of the vehicle in topical treatment adherence remains to be elucidated. The
aim of this study is to analyze the influence of the pharmaceutical dosage form on …

Real-world use, perception, satisfaction, and adherence of calcipotriol and betamethasone dipropionate PAD-cream in patients with plaque psoriasis in Spain and …

JL López Estebaranz, H Kurzen… - Journal of Dermatological …, 2024‏ - Taylor & Francis
Background Psoriasis significantly impacts patients' quality of life (QoL). Dissatisfaction and
non-adherence are major barriers associated with topical treatments. A cream based on the …

Engaging psoriasis patients in adherence and outcomes to topical treatments: A summary from the Symposium 'Tailoring topical psoriasis treatments to patients' …

A Bewley, P van de Kerkhof - Journal of the European Academy …, 2023‏ - Wiley Online Library
This article is based on a presentation given by authors at the Satellite Symposium titled
'Tailoring topical psoriasis treatments to patients' needs and expectations' held during the …

An anchored matching-adjusted indirect comparison of fixed-dose combination calcipotriol and betamethasone dipropionate (Cal/BDP) cream versus Cal/BDP foam …

A Bewley, E Barker, H Baker, W Green… - Journal of …, 2022‏ - Taylor & Francis
Objectives To undertake a comparison of Cal/BDP cream versus foam for the treatment of
plaque psoriasis, with cross-trial population differences accounted for. Materials and …

Burden of topical treatments in psoriasis and preferred criteria of choice: a survey-based evaluation of patients in Europe

A Bewley, L Hiribarne, J Galván, S Mburu - Dermatology and Therapy, 2024‏ - Springer
Introduction Topical treatments (TT) are widely used in psoriasis management. While
psoriasis itself has been associated with diminished quality of life and mental well-being, the …

Calcipotriol and betamethasone dipropionate cream based on PAD technology for the treatment of plaque psoriasis: a narrative review

T Torres, J Galván, N Crutchley, M Praestegaard… - Dermatology and …, 2023‏ - Springer
Topical treatment plays a crucial role in psoriasis management, with non-adherence being a
major barrier to treatment success. The fixed-dose combination of calcipotriol (CAL) and …

Sensory properties analysis of a calcipotriol and betamethasone dipropionate cream vehicle formulated with an innovative PAD Technology for the treatment of …

N García, P Guiró, J Galván, N Crutchley… - Drugs in …, 2023‏ - pmc.ncbi.nlm.nih.gov
Background In psoriasis, poor treatment adherence is frequently related to low efficacy and
limited cosmetic acceptability from the patients' perspective. This study aimed to characterize …

Goals and benefits in topical treatment for psoriasis: development and pilot validation of a patient-reported outcomes tool, the Patient Benefit Index for Topical …

C Blome, L Hülswitt, A Meineke… - British Journal of …, 2024‏ - academic.oup.com
Background Topical agents are an essential component of psoriasis therapy. Objectives To
develop a new version of the patient-reported Patient Benefit Index assessing the …