The Role of l-Carnitine in Mitochondria, Prevention of Metabolic Inflexibility and Disease Initiation

MA Virmani, M Cirulli - International journal of molecular sciences, 2022 - mdpi.com
Mitochondria control cellular fate by various mechanisms and are key drivers of cellular
metabolism. Although the main function of mitochondria is energy production, they are also …

L-carnitine and acylcarnitines: mitochondrial biomarkers for precision medicine

MR McCann, MV George De la Rosa, GR Rosania… - Metabolites, 2021 - mdpi.com
Biomarker discovery and implementation are at the forefront of the precision medicine
movement. Modern advances in the field of metabolomics afford the opportunity to readily …

Role of the microbiome in gut-heart-kidney cross talk

G Glorieux, SK Nigam, R Vanholder… - Circulation …, 2023 - Am Heart Assoc
Homeostasis is a prerequisite for health. When homeostasis becomes disrupted, dysfunction
occurs. This is especially the case for the gut microbiota, which under normal conditions …

[HTML][HTML] l-carnitine: Nutrition, pathology, and health benefits

AH Alhasaniah - Saudi Journal of Biological Sciences, 2023 - Elsevier
Carnitine is a medically needful nutrient that contributes in the production of energy and the
metabolism of fatty acids. Bioavailability is higher in vegetarians than in people who eat …

[HTML][HTML] The gut microbiota derived metabolite trimethylamine N-oxide: its important role in cancer and other diseases

Y Zhou, Y Zhang, S **, J Lv, M Li, N Feng - Biomedicine & …, 2024 - Elsevier
An expanding body of research indicates a correlation between the gut microbiota and
various diseases. Metabolites produced by the gut microbiota act as mediators between the …

Role of carnitine in non-alcoholic fatty liver disease and other related diseases: an update

N Li, H Zhao - Frontiers in medicine, 2021 - frontiersin.org
Carnitine is an amino acid-derived substance that coordinates a wide range of biological
processes. Such functions include transport of long-chain fatty acids from the cytoplasm to …

Carnitine in human muscle bioenergetics: can carnitine supplementation improve physical exercise?

A Gnoni, S Longo, GV Gnoni, AM Giudetti - Molecules, 2020 - mdpi.com
l-Carnitine is an amino acid derivative widely known for its involvement in the transport of
long-chain fatty acids into the mitochondrial matrix, where fatty acid oxidation occurs …

Filamentous fungi for sustainable vegan food production systems within a circular economy: Present status and future prospects

MK Awasthi, V Kumar, C Hellwig, R Wikandari… - Food Research …, 2023 - Elsevier
Filamentous fungi serve as potential candidates in the production of different value-added
products. In the context of food, there are several advantages of using filamentous fungi for …

Organic cation transporters in human physiology, pharmacology, and toxicology

SL Samodelov, GA Kullak-Ublick, Z Gai… - International journal of …, 2020 - mdpi.com
Individual cells and epithelia control the chemical exchange with the surrounding
environment by the fine-tuned expression, localization, and function of an array of …

Biochemical markers for the diagnosis of mitochondrial fatty acid oxidation diseases

P Ruiz-Sala, L Peña-Quintana - Journal of Clinical Medicine, 2021 - mdpi.com
Mitochondrial fatty acid β-oxidation (FAO) contributes a large proportion to the body's energy
needs in fasting and in situations of metabolic stress. Most tissues use energy from fatty …