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[PDF][PDF] Satellite cells and skeletal muscle regeneration
Skeletal muscles are essential for vital functions such as movement, postural support,
breathing, and thermogenesis. Muscle tissue is largely composed of long, postmitotic …
breathing, and thermogenesis. Muscle tissue is largely composed of long, postmitotic …
Transcriptional enhancers: from properties to genome-wide predictions
Cellular development, morphology and function are governed by precise patterns of gene
expression. These are established by the coordinated action of genomic regulatory …
expression. These are established by the coordinated action of genomic regulatory …
Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease
RNA-guided genome editing with the CRISPR-Cas9 system has great potential for basic
and clinical research, but the determinants of targeting specificity and the extent of off-target …
and clinical research, but the determinants of targeting specificity and the extent of off-target …
Library construction for next-generation sequencing: overviews and challenges
SR Head, HK Komori, SA LaMere, T Whisenant… - …, 2014 - Taylor & Francis
High-throughput sequencing, also known as next-generation sequencing (NGS), has
revolutionized genomic research. In recent years, NGS technology has steadily improved …
revolutionized genomic research. In recent years, NGS technology has steadily improved …
ChIP–seq and beyond: new and improved methodologies to detect and characterize protein–DNA interactions
Chromatin immunoprecipitation experiments followed by sequencing (ChIP–seq) detect
protein–DNA binding events and chemical modifications of histone proteins. Challenges in …
protein–DNA binding events and chemical modifications of histone proteins. Challenges in …
Histone modifications for human epigenome analysis
Histones function both positively and negatively in the regulation of gene expression, mainly
governed by post-translational modifications on specific amino acid residues. Although …
governed by post-translational modifications on specific amino acid residues. Although …
Epigenetic basis of mental illness
Psychiatric disorders are complex multifactorial illnesses involving chronic alterations in
neural circuit structure and function as well as likely abnormalities in glial cells. While …
neural circuit structure and function as well as likely abnormalities in glial cells. While …
[HTML][HTML] Map** human epigenomes
As the second dimension to the genome, the epigenome contains key information specific to
every type of cells. Thousands of human epigenome maps have been produced in recent …
every type of cells. Thousands of human epigenome maps have been produced in recent …
Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer
Malignancies are characterized by extensive global reprogramming of epigenetic patterns,
including gains or losses in DNA methylation and changes to histone marks. Furthermore …
including gains or losses in DNA methylation and changes to histone marks. Furthermore …
Trans-omics: how to reconstruct biochemical networks across multiple 'omic'layers
We propose 'trans-omic'analysis for reconstructing global biochemical networks across
multiple omic layers by use of both multi-omic measurements and computational data …
multiple omic layers by use of both multi-omic measurements and computational data …