Neurotransmitters: The critical modulators regulating gut–brain axis

R Mittal, LH Debs, AP Patel, D Nguyen… - Journal of cellular …, 2017‏ - Wiley Online Library
Neurotransmitters, including catecholamines and serotonin, play a crucial role in
maintaining homeostasis in the human body. Studies on these neurotransmitters mainly …

Targeting the gut-liver axis in liver disease

R Wiest, A Albillos, M Trauner, JS Bajaj, R Jalan - Journal of hepatology, 2017‏ - Elsevier
The gut-liver axis is widely implicated in the pathogenesis of liver diseases, where it is
increasingly the focus of clinical research. Recent studies trialling an array of therapeutic …

The double life of a B-1 cell: self-reactivity selects for protective effector functions

N Baumgarth - Nature Reviews Immunology, 2011‏ - nature.com
During their development, B and T cells with self-reactive antigen receptors are generally
deleted from the repertoire to avoid autoimmune diseases. Paradoxically, innate-like B-1 …

The microbiome and regulation of mucosal immunity

AJ McDermott, GB Huffnagle - Immunology, 2014‏ - Wiley Online Library
The gastrointestinal tract is a mucosal surface constantly exposed to foreign antigens and
microbes, and is protected by a vast array of immunologically active structures and cells …

The relationship between intestinal microbiota and the central nervous system in normal gastrointestinal function and disease

SM Collins, P Bercik - Gastroenterology, 2009‏ - Elsevier
Although many people are aware of the communication that occurs between the
gastrointestinal (GI) tract and the central nervous system, fewer know about the ability of the …

Dendritic cells in intestinal immune regulation

JL Coombes, F Powrie - Nature reviews immunology, 2008‏ - nature.com
A breakdown in intestinal homeostasis can result in chronic inflammatory diseases of the gut
including inflammatory bowel disease, coeliac disease and allergy. Dendritic cells, through …

Probiotics, prebiotics, and synbiotics: gut and beyond

U Vyas, N Ranganathan - Gastroenterology research and …, 2012‏ - Wiley Online Library
The human intestinal tract has been colonized by thousands of species of bacteria during
the coevolution of man and microbes. Gut‐borne microbes outnumber the total number of …

Lactogenic immunity and vaccines for porcine epidemic diarrhea virus (PEDV): Historical and current concepts

SN Langel, FC Paim, KM Lager, AN Vlasova, LJ Saif - Virus research, 2016‏ - Elsevier
Morbidity, mortality, and loss of productivity from enteric diseases in neonatal piglets cost
swine producers millions of dollars annually. In 2013–2014, the porcine epidemic diarrhea …

Stress at the intestinal surface: catecholamines and mucosa–bacteria interactions

M Lyte, L Vulchanova, DR Brown - Cell and tissue research, 2011‏ - Springer
Psychological stress has profound effects on gastrointestinal function, and investigations
over the past few decades have examined the mechanisms by which neural and hormonal …

Human gut microbiota and its relationship to health and disease

TC Wallace, F Guarner, K Madsen, MD Cabana… - Nutrition …, 2011‏ - academic.oup.com
Probiotics are live microorganisms that confer a health benefit on the host when
administered in appropriate amounts. Over 700 randomized, controlled, human studies have …