Tumor microenvironment as a “game changer” in cancer radiotherapy

M Jarosz-Biej, R Smolarczyk, T Cichoń… - International journal of …, 2019 - mdpi.com
Radiotherapy (RT), besides cancer cells, also affects the tumor microenvironment (TME):
tumor blood vessels and cells of the immune system. It damages endothelial cells and …

Functionalized chitosan for cancer nano drug delivery

Y Zaiki, A Iskandar, TW Wong - Biotechnology Advances, 2023 - Elsevier
Chitosan is a biotechnological derivative of chitin receiving a widespread pharmaceutical
and biomedical applications. It can be used to encapsulate and deliver cancer therapeutics …

Radiation-induced bystander and abscopal effects: important lessons from preclinical models

E Daguenet, S Louati, AS Wozny, N Vial, M Gras… - British journal of …, 2020 - nature.com
Radiotherapy is a pivotal component in the curative treatment of patients with localised
cancer and isolated metastasis, as well as being used as a palliative strategy for patients …

Stress management in plants: examining provisional and unique dose-dependent responses

M Georgieva, V Vassileva - International Journal of Molecular Sciences, 2023 - mdpi.com
The purpose of this review is to critically evaluate the effects of different stress factors on
higher plants, with particular attention given to the typical and unique dose-dependent …

Immunomodulatory effects of radiotherapy

S Kumari, S Mukherjee, D Sinha, S Abdisalaam… - International journal of …, 2020 - mdpi.com
Radiation therapy (RT), an integral component of curative treatment for many malignancies,
can be administered via an increasing array of techniques. In this review, we summarize the …

The use of nanomaterials in advancing photodynamic therapy (PDT) for deep-seated tumors and synergy with radiotherapy

D Dinakaran, BC Wilson - Frontiers in Bioengineering and …, 2023 - frontiersin.org
Photodynamic therapy (PDT) has been under development for at least 40 years. Multiple
studies have demonstrated significant anti-tumor efficacy with limited toxicity concerns. PDT …

[HTML][HTML] A perspective on the radiopharmaceutical requirements for imaging and therapy of glioblastoma

J Bolcaen, J Kleynhans, S Nair, J Verhoeven… - Theranostics, 2021 - ncbi.nlm.nih.gov
Despite numerous clinical trials and pre-clinical developments, the treatment of glioblastoma
(GB) remains a challenge. The current survival rate of GB averages one year, even with an …

Divide and conquer: spatially fractionated radiation therapy

Y Prezado - Expert reviews in molecular medicine, 2022 - cambridge.org
Spatially fractionated radiation therapy (SFRT) challenges some of the classical dogmas in
conventional radiotherapy. The highly modulated spatial dose distributions in SFRT have …

[HTML][HTML] Empirical relative biological effectiveness (RBE) for mandible osteoradionecrosis (ORN) in head and neck cancer patients treated with pencil-beam-scanning …

Y Yang, OM Muller, SE Schild, M Bues, M Fatyga… - Frontiers in …, 2022 - frontiersin.org
Purpose To retrospectively investigate empirical relative biological effectiveness (RBE) for
mandible osteoradionecrosis (ORN) in head and neck (H&N) cancer patients treated with …

[HTML][HTML] Safety and efficacy of lattice radiotherapy in voluminous non-small cell lung cancer

BE Amendola, NC Perez, X Wu, MA Amendola… - Cureus, 2019 - ncbi.nlm.nih.gov
Objective Lattice radiotherapy (LRT) is a novel technique of delivering heterogeneous doses
of radiation to voluminous tumors not amenable to surgery. Built from the conventional two …