Biomarkers: Promising and valuable tools towards diagnosis, prognosis and treatment of Covid-19 and other diseases

A Bodaghi, N Fattahi, A Ramazani - Heliyon, 2023‏ - cell.com
The use of biomarkers as early warning systems in the evaluation of disease risk has
increased markedly in the last decade. Biomarkers are indicators of typical biological …

High-resolution native mass spectrometry

S Tamara, MA den Boer, AJR Heck - Chemical reviews, 2021‏ - ACS Publications
Native mass spectrometry (MS) involves the analysis and characterization of
macromolecules, predominantly intact proteins and protein complexes, whereby as much as …

Ovarian cancer biomarkers: moving forward in early detection

VDB Bonifácio - Tumor Microenvironment: The Main Driver of Metabolic …, 2020‏ - Springer
Ovarian cancer is a silent cancer which rate survival mainly relays in early stage detection.
The discovery of reliable ovarian cancer biomarkers plays a crucial role in the disease …

Human body fluid proteome analysis

S Hu, JA Loo, DT Wong - Proteomics, 2006‏ - Wiley Online Library
The focus of this article is to review the recent advances in proteome analysis of human
body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar …

Mass spectrometry as a diagnostic and a cancer biomarker discovery tool: opportunities and potential limitations

EP Diamandis - Molecular & Cellular Proteomics, 2004‏ - mcponline.org
Serum proteomic profiling, by using surfaced-enhanced laser desorption/ionization-time-of-
flight mass spectrometry, is one of the most promising new approaches for cancer …

Haptoglobin as a Biomarker

SN Naryzny, OK Legina - Biochemistry (Moscow), Supplement Series B …, 2021‏ - Springer
Haptoglobin (Hp) is a glycoprotein that binds free hemoglobin (Hb) in plasma and plays a
critical role in tissue protection and prevention of oxidative damage. Besides, it has some …

The early detection of ovarian cancer: from traditional methods to proteomics. Can we really do better than serum CA-125?

V Nossov, M Amneus, F Su, J Lang, JMT Janco… - American journal of …, 2008‏ - Elsevier
Ovarian cancer is the leading cause of death from gynecologic malignancy in the United
States. More than 80% of patients present with advanced disease, with 5 year survival rates …

Analysis of serum proteomic patterns for early cancer diagnosis: drawing attention to potential problems

EP Diamandis - Journal of the National Cancer Institute, 2004‏ - academic.oup.com
In a recent update (1) of already impressive data (2), it was reported that the use of
proteomic patterns in serum to diagnose ovarian and prostate cancers can achieve perfect …

Interplay of transcriptomics and proteomics

PS Hegde, IR White, C Debouck - Current opinion in biotechnology, 2003‏ - Elsevier
Despite the obvious attractions of parallel profiling of transcripts and proteins on a global
'omic'scale, there are practical and biological differences involved in their application …

Sample preparation for serum/plasma profiling and biomarker identification by mass spectrometry

JL Luque-Garcia, TA Neubert - Journal of Chromatography A, 2007‏ - Elsevier
In this article, we present an overview of the different strategies for sample preparation for
identification by mass spectrometry (MS) of biomarkers from serum and/or plasma. We …