Chagas heart disease is an inflammatory cardiomyopathy that develops in approximately
one-third of people infected with the protozoan parasite Trypanosoma cruzi. One way T …

Trypanosoma cruzi interacts with the different arms of the innate and adaptive host's immune
response in a very complex and flowery manner. The history of host-parasite co-evolution …

Introduction: Three major advances have led to increase in length and quality of human life:
increased food production, improved sanitation and induction of specific adaptive immune …

Introduction Chronic infection with the protozoal parasite Trypanosoma cruzi leads to a
progressive cardiac disease, known as chronic Chagasic cardiomyopathy (CCC). A new …

BACKGROUND Trypanosoma cruzi, which causes Chagas disease (CD), is a versatile
haemoparasite that uses several strategies to evade the host's immune response, including …

Chagas disease (CD), caused by Trypanosoma cruzi, affects approximately 6 to 7 million
people in Latin America, with cardiomyopathy being the clinical manifestation most …

In the late phase of Trypanosoma cruzi infection, parasite persistence and an exaggerated
immune response accompanied by oxidative stress play a crucial role in the genesis of …

Chronic Chagas heart disease (CCHD affects about 30% of patients with chronic Chagas
disease (CCD). Systemic arterial hypertension (SAH) afflicts about 25% of patients with …

Chagasic chronic cardiomyopathy (CCC) is the primary clinical manifestation of Chagas
disease (CD), caused by Trypanosoma cruzi. Current therapeutic options for CD are limited …

Background Cardiac fibrosis is a consequence of chronic chagasic cardiomyopathy (CCC).
In other cardiovascular diseases, the protagonist role of fibroblasts in cardiac fibrosis is well …