COVID-19: Transmission, prevention, and potential therapeutic opportunities

M Lotfi, MR Hamblin, N Rezaei - Clinica chimica acta, 2020 - Elsevier
The novel coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), remains a global challenge. Despite intense …

The pathogenesis and treatment of theCytokine Storm'in COVID-19

Q Ye, B Wang, J Mao - Journal of infection, 2020 - Elsevier
Cytokine storm is a general term applied to maladaptive cytokine release in response to
infection and other stimuli. The pathogenesis is complex but includes loss of regulatory …

Drug repurposing approach to fight COVID-19

TU Singh, S Parida, MC Lingaraju, M Kesavan… - Pharmacological …, 2020 - Springer
Currently, there are no treatment options available for the deadly contagious disease,
coronavirus disease 2019 (COVID-19). Drug repurposing is a process of identifying new …

The role of cytokines including interleukin-6 in COVID-19 induced pneumonia and macrophage activation syndrome-like disease

D McGonagle, K Sharif, A O'Regan, C Bridgewood - Autoimmunity reviews, 2020 - Elsevier
Severe COVID-19 associated pneumonia patients may exhibit features of systemic hyper-
inflammation designated under the umbrella term of macrophage activation syndrome …

[HTML][HTML] Type I and type III interferons–induction, signaling, evasion, and application to combat COVID-19

A Park, A Iwasaki - Cell host & microbe, 2020 - cell.com
Coronavirus disease 2019 (COVID-19) is a global pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Without approved antiviral therapeutics …

The epidemiology, diagnosis and treatment of COVID-19

P Zhai, Y Ding, X Wu, J Long, Y Zhong, Y Li - International journal of …, 2020 - Elsevier
In December 2019, the outbreak of the novel coronavirus disease (COVID-19) in China
spread worldwide, becoming an emergency of major international concern. SARS-CoV-2 …

Clinical features of 69 cases with coronavirus disease 2019 in Wuhan, China

Z Wang, B Yang, Q Li, L Wen… - Clinical infectious …, 2020 - academic.oup.com
Abstract Background From December 2019 to February 2020, 2019 severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has caused a serious outbreak of coronavirus …

Clinical features and treatment of COVID‐19 patients in northeast Chongqing

S Wan, YI **ang, W Fang, Y Zheng, B Li… - Journal of medical …, 2020 - Wiley Online Library
The outbreak of the novel coronavirus in China (SARS‐CoV‐2) that began in December
2019 presents a significant and urgent threat to global health. This study was conducted to …

Therapeutic options for the 2019 novel coronavirus (2019-nCoV)

G Li, E De Clercq - Nature reviews Drug discovery, 2020 - nature.com
Therapeutic options for the 2019 novel coronavirus (2019-nCoV) Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

COVID-19 and the heart

A Akhmerov, E Marbán - Circulation research, 2020 - Am Heart Assoc
Infection with the severe acute respiratory syndrome novel coronavirus produces a clinical
syndrome known as 2019 novel coronavirus disease (COVID-19). When severe, COVID-19 …