Microfluidics: Fluid physics at the nanoliter scale

TM Squires, SR Quake - Reviews of modern physics, 2005 - APS
Microfabricated integrated circuits revolutionized computation by vastly reducing the space,
labor, and time required for calculations. Microfluidic systems hold similar promise for the …

Microfluidic large-scale integration: the evolution of design rules for biological automation

J Melin, SR Quake - Annu. Rev. Biophys. Biomol. Struct., 2007 - annualreviews.org
Microfluidic large-scale integration (mLSI) refers to the development of microfluidic chips
with thousands of integrated micromechanical valves and control components. This …

Mechanical characterization of bulk Sylgard 184 for microfluidics and microengineering

ID Johnston, DK McCluskey, CKL Tan… - Journal of …, 2014 - iopscience.iop.org
Polydimethylsiloxane (PDMS) elastomers are extensively used for soft lithographic
replication of microstructures in microfluidic and micro-engineering applications. Elastomeric …

[BOOK][B] Handbook of nanoscience, engineering, and technology

WA Goddard III, D Brenner, SE Lyshevski, GJ Iafrate - 2002 - taylorfrancis.com
Nanotechnology, science, and engineering spearhead the 21st century revolution that is
leading to fundamental breakthroughs in the way materials, devices, and systems are …

Microvalves and micropumps for BioMEMS

AK Au, H Lai, BR Utela, A Folch - Micromachines, 2011 - mdpi.com
This review presents an extensive overview of a large number of microvalve and micropump
designs with great variability in performance and operation. The performance of a given …

DNA confinement in nanochannels: physics and biological applications

W Reisner, JN Pedersen… - Reports on progress in …, 2012 - iopscience.iop.org
DNA is the central storage molecule of genetic information in the cell, and reading that
information is a central problem in biology. While sequencing technology has made …

A quick and accurate method to determine the Poisson's ratio and the coefficient of thermal expansion of PDMS

A Müller, MC Wapler, U Wallrabe - Soft Matter, 2019 - pubs.rsc.org
We present a new and accurate method to determine the Poisson's ratio of PDMS, using
thermal expansion and an optical surface profilometer. The Poisson's ratio of Sylgard 184 …

Mechanical properties of silicones for MEMS

F Schneider, T Fellner, J Wilde… - … of Micromechanics and …, 2008 - iopscience.iop.org
This paper focuses on the mechanical properties of polydimethylsiloxane (PDMS) relevant
for microelectromechanical system (MEMS) applications. In view of the limited amount of …

Microfluidic very large scale integration (mVLSI) with integrated micromechanical valves

IE Araci, SR Quake - Lab on a Chip, 2012 - pubs.rsc.org
Microfluidic chips with a high density of control elements are required to improve device
performance parameters, such as throughput, sensitivity and dynamic range. In order to …

An integrated AC electrokinetic pump in a microfluidic loop for fast and tunable flow control

V Studer, A Pépin, Y Chen, A Ajdari - Analyst, 2004 - pubs.rsc.org
We have built a dedicated lab on a chip to study the performance of an integrated
electrokinetic micropump, driven by a low voltage AC signal. This micropump consists of an …