Major depressive disorder
Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …
Genetics and pathogenesis of Parkinson's syndrome
Parkinson's disease (PD) is clinically, pathologically, and genetically heterogeneous,
resisting distillation to a single, cohesive disorder. Instead, each affected individual develops …
resisting distillation to a single, cohesive disorder. Instead, each affected individual develops …
A cross-population atlas of genetic associations for 220 human phenotypes
Current genome-wide association studies do not yet capture sufficient diversity in
populations and scope of phenotypes. To expand an atlas of genetic associations in non …
populations and scope of phenotypes. To expand an atlas of genetic associations in non …
Maternal immune activation and neuroinflammation in human neurodevelopmental disorders
Maternal health during pregnancy plays a major role in sha** health and disease risks in
the offspring. The maternal immune activation hypothesis proposes that inflammatory …
the offspring. The maternal immune activation hypothesis proposes that inflammatory …
[HTML][HTML] The world federation of ADHD international consensus statement: 208 evidence-based conclusions about the disorder
Background Misconceptions about ADHD stigmatize affected people, reduce credibility of
providers, and prevent/delay treatment. To challenge misconceptions, we curated findings …
providers, and prevent/delay treatment. To challenge misconceptions, we curated findings …
Neurodevelopment of the association cortices: Patterns, mechanisms, and implications for psychopathology
The human brain undergoes a prolonged period of cortical development that spans multiple
decades. During childhood and adolescence, cortical development progresses from lower …
decades. During childhood and adolescence, cortical development progresses from lower …
Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction
Behaviors and disorders related to self-regulation, such as substance use, antisocial
behavior and attention-deficit/hyperactivity disorder, are collectively referred to as …
behavior and attention-deficit/hyperactivity disorder, are collectively referred to as …
[HTML][HTML] Pharmacotherapy of anxiety disorders: current and emerging treatment options
Anxiety disorders are the most prevalent psychiatric disorders and a leading cause of
disability. While there continues to be expansive research in posttraumatic stress disorder …
disability. While there continues to be expansive research in posttraumatic stress disorder …
The genetic basis of major depressive disorder
J Flint - Molecular psychiatry, 2023 - nature.com
The genetic dissection of major depressive disorder (MDD) ranks as one of the success
stories of psychiatric genetics, with genome-wide association studies (GWAS) identifying …
stories of psychiatric genetics, with genome-wide association studies (GWAS) identifying …
Maternal acute and chronic inflammation in pregnancy is associated with common neurodevelopmental disorders: a systematic review
Inflammation is increasingly recognized as a cause or consequence of common problems of
humanity including obesity, stress, depression, pollution and disease states such as …
humanity including obesity, stress, depression, pollution and disease states such as …