TGF-β1 signalling in Alzheimer's pathology and cytoskeletal reorganization: a specialized Tau perspective
M Kapoor, S Chinnathambi - Journal of Neuroinflammation, 2023 - Springer
Microtubule-associated protein, Tau has been implicated in Alzheimer's disease for its
detachment from microtubules and formation of insoluble intracellular aggregates within the …
detachment from microtubules and formation of insoluble intracellular aggregates within the …
[HTML][HTML] Mechanical tumor microenvironment and transduction: cytoskeleton mediates cancer cell invasion and metastasis
X Li, J Wang - International journal of biological sciences, 2020 - ncbi.nlm.nih.gov
Metastasis is a complicated, multistep process that is responsible for over 90% of cancer-
related death. Metastatic disease or the movement of cancer cells from one site to another …
related death. Metastatic disease or the movement of cancer cells from one site to another …
Cellular dynamics of EMT: lessons from live in vivo imaging of embryonic development
JD Amack - Cell Communication and Signaling, 2021 - Springer
Epithelial-mesenchymal transition (EMT) refers to a process in which epithelial cells lose
apical-basal polarity and loosen cell–cell junctions to take on mesenchymal cell …
apical-basal polarity and loosen cell–cell junctions to take on mesenchymal cell …
[HTML][HTML] Autophagy modulates transforming growth factor beta 1 induced epithelial to mesenchymal transition in non-small cell lung cancer cells
Lung cancer is considered one of the most frequent causes of cancer-related death
worldwide and Non-Small Cell Lung Cancer (NSCLC) accounts for 80% of all lung cancer …
worldwide and Non-Small Cell Lung Cancer (NSCLC) accounts for 80% of all lung cancer …
[HTML][HTML] Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/syndecan-1/TGF-β autocrine loop
Abstract Sphingosine-1-phosphate (S1P) induces epithelial–mesenchymal transition (EMT)
in hepatocellular carcinoma (HCC). However, its underlying mechanism remains largely …
in hepatocellular carcinoma (HCC). However, its underlying mechanism remains largely …
[HTML][HTML] Molecular basis of hepatocellular carcinoma induced by hepatitis C virus infection
Present study outlines a comprehensive view of published information about the underlying
mechanisms operational for progression of chronic hepatitis C virus (HCV) infection to …
mechanisms operational for progression of chronic hepatitis C virus (HCV) infection to …
The role of cullin 5-containing ubiquitin ligases
F Okumura, A Joo-Okumura, K Nakatsukasa, T Kamura - Cell division, 2016 - Springer
The suppressor of cytokine signaling (SOCS) box consists of the BC box and the cullin 5
(Cul5) box, which interact with Elongin BC and Cul5, respectively. SOCS box-containing …
(Cul5) box, which interact with Elongin BC and Cul5, respectively. SOCS box-containing …
Epithelial–mesenchymal transition in the formation of hypertrophic scars and keloids
FL Yuan, ZL Sun, Y Feng, SY Liu, Y Du… - Journal of cellular …, 2019 - Wiley Online Library
Abnormal wound healing is likely to induce the formation of hypertrophic scars and keloids,
which leads to dysfunction, deformity, and mental problem in the patients. Despite the …
which leads to dysfunction, deformity, and mental problem in the patients. Despite the …
Distinct transcriptional changes distinguish efficient and poor remyelination in multiple sclerosis
JQA Chen, NB McNamara, HJ Engelenburg… - Brain, 2024 - academic.oup.com
Multiple sclerosis (MS) is a highly heterogeneous disease with varying remyelination
potential across individuals and between lesions. However, the molecular mechanisms …
potential across individuals and between lesions. However, the molecular mechanisms …
Unresolved complexity in the gene regulatory network underlying EMT
DP Lavin, VK Tiwari - Frontiers in oncology, 2020 - frontiersin.org
Epithelial to mesenchymal transition (EMT) is the process whereby a polarized epithelial cell
ceases to maintain cell-cell contacts, loses expression of characteristic epithelial cell …
ceases to maintain cell-cell contacts, loses expression of characteristic epithelial cell …