Highlights•We now have metabolic network models; the metabolome is represented by their
nodes.•Metabolite levels are sensitive to changes in enzyme activities.•Drugs hitchhike on …

Atherosclerosis is currently considered an inflammatory disease. Much attention has been
focused on the potential role of inflammatory mediators as prognostic/diagnostic markers or …

Macrobrachium nipponense is an economically and nutritionally important species
threatened by ambient superfluous nitrite. De novo RNA-Seq was used to explore the …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection has rapidly
spread across the world since its first emergence in China in late 2019. It is a major public …

In this study, the intrinsic surface-enhanced Raman spectroscopy (SERS)-based approach
coupled with chemometric analysis was adopted to establish the biochemical fingerprint of …

This review provides an updated overview of the emerging roles of neopterin derivatives in
atherosclerosis. Neopterin, a metabolite of guanosine triphosphate, is produced by …

The prevalence of age-related comorbidities is increased in people living with HIV, even in
those well-controlled on combination antiretroviral therapy (ART). Persistent immune …

A simplified method for analyzing tryptophan (Trp) and its metabolites in human plasma was
developed using liquid chromatography–electrospray ionization tandem mass spectrometry …

Background Neopterin is a pyrazino-pyrimidine compound which is used as a marker of cell-
mediated immunity in a variety of diseases. It is known that neopterin levels increase in …

Background Neopterin, a marker of inflammation and cellular immune response, is elevated
in conditions of T-cell or macrophages activation. Diabetic peripheral neuropathy (DPN) is …