Synthesis and intensive characterization for novel Zn (II), Pd (II), Cr (III) and VO (II)-Schiff base complexes; DNA-interaction, DFT, drug-likeness and molecular docking …

AM Abu-Dief, RM El-Khatib, FS Aljohani… - Journal of Molecular …, 2021 - Elsevier
A novel bioactive series was synthesized from Zn (II), Pd (II), Cr (III) and VO (II) ions with a
new Schiff base derivative (HNP)[HNP= 1-(Pyrimidin-2-yliminomethyl)-naphthalen-2-ol]. The …

Sustainable mechanosynthesis of biologically active molecules

O Bento, F Luttringer, T Mohy El Dine… - European Journal of …, 2022 - Wiley Online Library
Synthetic mechanochemistry, the use of mechanical force produced by milling, grinding or
extruding, as an activation technique, provides access to chemical entities of all kinds. This …

A review of hydrazide-hydrazone metal complexes' antitumor potential

N Ribeiro, I Correia - Frontiers in Chemical Biology, 2024 - frontiersin.org
Cancer inflicts a tremendous burden on modern society, and more effective and selective
treatments need to be developed. Metallodrugs have been extensively explored as …

Synthesis and characterization of Fe (III), Pd (II) and Cu (II)-thiazole complexes; DFT, pharmacophore modeling, in-vitro assay and DNA binding studies

AM Abu-Dief, NM El-Metwaly, SO Alzahrani… - Journal of Molecular …, 2021 - Elsevier
New pharmacologically active complexes were prepared from Pd (II), Fe (III), and Cu (II) ions
with 2-amino-6-oxo-3-(piperidinylamidino)-4-(4methoxyphenyl)-6, 7-dihydro-pyrano [2, 3-d] …

Structural inspection for novel Pd (II), VO (II), Zn (II) and Cr (III)-azomethine metal chelates: DNA interaction, biological screening and theoretical treatments

FS Aljohani, AM Abu-Dief, RM El-Khatib… - Journal of Molecular …, 2021 - Elsevier
An alternative sequence of bioactive series, using novel Schiff base derivative (1-Quinolin-8-
yliminomethyl-naphthalen-2-ol), was produced (HNQ). Elements analysis, molar …

Optimization for synthesized quinoline-based Cr3+, VO2+, Zn2+ and Pd2+ complexes: DNA interaction, biological assay and in-silico treatments for verification

HA Al-Abdulkarim, RM El-khatib, FS Aljohani… - Journal of Molecular …, 2021 - Elsevier
A novel momonuclear metal chelates were derived from Zn (II), Pd (II), VO (II) and Cr (III) ions
with azomethine (BSQ)[BSQ= 4-Bromo-2-(quinolin-8-yliminomethyl)-phenol] ligand. The …

Synthesis and characterization of new thiazole-based Co (II) and Cu (II) complexes; therapeutic function of thiazole towards COVID-19 in comparing to current …

SA Almalki, TM Bawazeer, B Asghar, A Alharbi… - Journal of molecular …, 2021 - Elsevier
Two thiazole-based complexes were prepared from Co (II) and Cu (II) ions. The new ligand
and its complexes were fully characterized by analytical and spectral techniques. The ligand …

Green synthesis for new Co (II), Ni (II), Cu (II) and Cd (II) hydrazone-based complexes; characterization, biological activity and electrical conductance of nano-sized …

SD Al-Qahtani, A Alsoliemy, SJ Almehmadi… - Journal of Molecular …, 2021 - Elsevier
A series of new hydrazone complexes were prepared and perfectly elucidated to be 1: 1
molar ratio with Cd (II) complex, while 1: 2 (M: L) with Co (II), Ni (II) and Cu (II) complexes …

Development of new thiazole‐guanidine complexes as rapid and recoverable catalysts for the synthesis of 6‐piperidin‐dihydro‐thia‐hexaaza‐s‐indacene derivatives …

MAEAAA El‐Remaily, O Elhady… - Applied …, 2024 - Wiley Online Library
In this study, the focus was on synthesizing metal chelates of Fe (III), Ni (II), and Pd (II) using
thiazole‐guanidine derivatives. Various spectral and analytical methods were employed to …

Elucidating of new hydrazide-based complexes derived from Pd (II), Cu (II) and Cd (II) ions: studies concerning spectral, DFT, Hirshfeld-crystal, biological screening …

O Alaysuy, HM Abumelha, A Alsoliemy… - Journal of Molecular …, 2022 - Elsevier
A new hydrazide ligand (HL) was characterized to be used for synthesis of some bivalent
complexes via a green approach that free from hazard solvents. All synthesizes were …