Imaging the limbic system in Parkinson's disease—a review of limbic pathology and clinical symptoms

M Banwinkler, H Theis, S Prange, T van Eimeren - Brain sciences, 2022 - mdpi.com
The limbic system describes a complex of brain structures central for memory, learning, as
well as goal directed and emotional behavior. In addition to pathological studies, recent …

Sex and gender differences in Parkinson's disease

R Patel, K Kompoliti - Neurologic Clinics, 2023 - neurologic.theclinics.com
Parkinson's disease (PD) is the second most common neurodegenerative disease affecting
older adults, and it is approximately twice as common in males compared with females. 1 …

Gender gap in deep brain stimulation for Parkinson's disease

ST Jost, L Strobel, A Rizos, PA Loehrer… - npj Parkinson's …, 2022 - nature.com
Previous studies have shown less access to deep brain stimulation (DBS) for Parkinson's
disease (PD) in women compared to men raising concerns about a potential gender gap …

[HTML][HTML] Sex representation in neurodegenerative and psychiatric disorders' preclinical and clinical studies

M DuMont, A Agostinis, K Singh, E Swan, Y Buttle… - Neurobiology of …, 2023 - Elsevier
Many studies show the importance of biological sex for the onset, progression, and
response to treatment in brain disorders. In line with these reports, health agencies have …

X-vectors: new quantitative biomarkers for early Parkinson's disease detection from speech

L Jeancolas, D Petrovska-Delacrétaz… - Frontiers in …, 2021 - frontiersin.org
Many articles have used voice analysis to detect Parkinson's disease (PD), but few have
focused on the early stages of the disease and the gender effect. In this article, we have …

Sex differences in Parkinson's disease: from bench to bedside

MC Russillo, V Andreozzi, R Erro, M Picillo, M Amboni… - Brain sciences, 2022 - mdpi.com
Background: Parkinson's disease (PD) is the second most common neurodegenerative
disorder after Alzheimer's disease and gender differences have been described on several …

Increased palmitoylation improves estrogen receptor alpha–dependent hippocampal synaptic deficits in a mouse model of synucleinopathy

TE Moors, S Li, TD McCaffery, GPH Ho… - Science …, 2023 - science.org
Parkinson's disease (PD) is characterized by conversion of soluble α-synuclein (αS) into
intraneuronal aggregates and degeneration of neurons and neuronal processes. Indications …

Age and sex differentially shape brain networks in Parkinson's disease

Z Chen, B Wu, G Li, L Zhou, L Zhang… - CNS Neuroscience & …, 2023 - Wiley Online Library
Aims Age and sex are important individual factors modifying the clinical symptoms of
patients with Parkinson's disease (PD). Our goal is to evaluate the effects of age and sex on …

Sex Differences in Brain and Cognition in de novo Parkinson's Disease

J Oltra, C Uribe, A Campabadal, A Inguanzo… - Frontiers in Aging …, 2022 - frontiersin.org
Background and Objective: Brain atrophy and cognitive impairment in neurodegenerative
diseases are influenced by sex. We aimed to investigate sex differences in brain atrophy …

Alteration of the cortical morphology in classical trigeminal neuralgia: voxel-, deformation-, and surface-based analysis

X Ge, L Wang, L Pan, H Ye, X Zhu, S Fan… - The Journal of …, 2023 - Springer
Objective This study aimed to combine voxel-based morphometry, deformation-based
morphometry, and surface-based morphometry to analyze gray matter volume and cortex …