Maintenance of genome integrity is a key issue for all living organisms. Cells are constantly
exposed to DNA damage due to replication or transcription, cellular metabolic activities …

Developmental and environmental signals converge on cell cycle machinery to achieve
proper and flexible organogenesis under changing environments. Studies on the plant cell …

While transformation of the major monocot crops is currently possible, the process typically
remains confined to one or two genotypes per species, often with poor agronomics, and …

The CRISPR/Cas9 system has greatly improved our ability to engineer targeted mutations in
eukaryotic genomes. While CRISPR/Cas9 appears to work universally, the efficiency of …

A great many cell types are necessary for the myriad capabilities of complex, multicellular
organisms. One interesting aspect of this diversity of cell type is that many cells in diploid …

Cell cycle regulation is of pivotal importance for plant growth and development. Although
plant cell division shares basic mechanisms with all eukaryotes, plants have evolved novel …

Cambridge, Massachusetts 02142 mosomal configuration. In endoreplication cell cycles, or
endocycles, S Molecular studies from the past decade have revealed phases alternate with …

The Arabidopsis thaliana hypocotyl is widely used to study the effects of light and plant
growth factors on cell elongation. To provide a framework for the molecular-genetic analysis …

Relative quantities of DNA in individual nuclei of stem and leaf epidermal cells of
Arabidopsis were measured microspectrofluorometrically using epidermal peels. The …

Activation of cell division in the root apical meristem after germination is essential for
postembryonic root development. Arabidopsis plants homozygous for a mutation in the …