In accordance with the comorbidity-inflammation paradigm, comorbidities and especially
metabolic comorbidities are presumed to drive development and severity of heart failure with …

Introduction: COVID-19 is causing considerable morbidity and mortality worldwide. Serious
respiratory complications aside, the heart is also frequently involved. The mechanisms and …

Background: Early heart failure (HF) recognition can reduce morbidity, yet HF is often initially
diagnosed only after a patient clinically worsens. We sought to identify characteristics that …

Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality
despite aggressive treatment of traditional risk factors. Chronic inflammation plays an …

Cardiovascular disease (CVD) is a leading cause of global morbidity and mortality. Cancer
survivors have significantly elevated risk of poor cardiovascular (CV) health outcomes due to …

Targeted prevention of heart failure (HF) remains a critical need given the high prevalence
of HF morbidity and mortality. Similar to risk-based prevention of atherosclerotic …

Background Coronary artery disease (CAD) is the most common cause of new-onset heart
failure (HF). Although guidelines recommend ischemic evaluation in this population, testing …

Background: Guidelines recommend identification of individuals at risk for heart failure (HF).
However, implementation of risk-based prevention strategies requires validation of HF …

Despite considerable advances in the field, heart failure (HF) still poses a significant disease
burden among affected individuals since it continues to cause high morbidity and mortality …

Atrial fibrillation (AF) is associated with exercise intolerance, stroke, and all-cause mortality.
However, whether this can be solely attributable to the arrhythmia itself or alternative …