Retinoids regulate a wide spectrum of cellular functions from the embryo throughout
adulthood, including cell differentiation, metabolic regulation, and inflammation. These traits …

Alloy based implants have made a great impact in the clinic and in preclinical research.
Immune responses are one of the major causes of failure of these implants in the clinic …

Tumor-infiltrating myeloid cells (TIMs) are key regulators in tumor progression, but the
similarity and distinction of their fundamental properties across different tumors remain …

Dendritic cells (DCs) are major regulators of adaptive immunity, as they are not only capable
to induce efficient immune responses, but are also crucial to maintain peripheral tolerance …

Skin, the largest organ in the human body, is a crucial protective barrier that plays essential
roles in thermoregulation, sensation, and immune defence. This complex organ undergoes …

Vitamin A is a fat-soluble vitamin that plays an important role in skin immunity. Deficiencies
in Vitamin A have been linked to impaired immune response and increased susceptibility to …

All–trans–retinoic acid (ATRA) has long been known to affect cell growth and differentiation.
To improve ATRA's therapeutic efficacy and pharmacodynamics, several delivery systems …

Atopic dermatitis (AD) is a common inflammation skin disease that involves dysregulated
interplay between immune cells and keratinocytes. Interleukin-38 (IL-38), a poorly …

Purpose: Transamniotic stem cell therapy (TRASCET) with mesenchymal stem cells (MSCs)
can induce spina bifida coverage with neoskin. We initiated a mechanistic analysis of this …

Background Complex interactions between the environment and the mucosal immune
system underlie inflammatory bowel disease (IBD). The involved cytokine signalling …