Recent advancements and developments in search of anti-tuberculosis agents: a quinquennial update and future directions

TM Dhameliya, KA Bhakhar, ND Gajjar, KA Patel… - Journal of Molecular …, 2022 - Elsevier
Tuberculosis (TB) has been considered as the highly chronic, contagious and infectious
disorder caused by Mycobacterium tuberculosis (Mtb). Every year more than 10 million …

Recent advancement in drug development of nitro(NO2)‐heterocyclic compounds as lead scaffolds for the treatment of Mycobacterium tuberculosis

CB Scarim, FR Pavan - Drug Development Research, 2022 - Wiley Online Library
Tuberculosis (TB) is an infectious disease caused predominantly by Mycobacterium
tuberculosis (Mtb). It was responsible for approximately 1.4 million deaths worldwide in …

Microwave-Assisted Copper (II)-Catalyzed Cascade Cyclization of 2-Propargylamino/Oxy-Arylaldehydes and O-Phenylenediamines: Access to Densely …

D Rajput, A Kumar, T Jandial… - The Journal of …, 2022 - ACS Publications
A highly efficient microwave-assisted copper (II)-catalyzed cyclization cascade was
established starting from readily accessible O/N-propargylated 2-hydroxy or 2 …

[HTML][HTML] In-silico investigation and drug likeliness studies of benzimidazole congeners: the new face of innovation

S Thapa, SL Nargund, MS Biradar, J Banerjee… - Informatics in Medicine …, 2023 - Elsevier
Background The primary driving force behind the development of several small molecules
for the treatment of tuberculosis is multi-drug resistance. A new fluorinated heterocyclic …

QSAR models for the acute toxicity of 1, 2, 4-triazole fungicides to zebrafish (Danio rerio) embryos

K Qiao, W Fu, Y Jiang, L Chen, S Li, Q Ye, W Gui - Environmental Pollution, 2020 - Elsevier
Abstract In recent decades, the 1, 2, 4-triazole fungicides are widely used for crop diseases
control, and their toxicity to wild lives and pollution to ecosystem have attracted more and …

Synthesis, Molecular Docking, Molecular Dynamic Simulation Studies, and Antitubercular Activity Evaluation of Substituted Benzimidazole Derivatives

S Thapa, MS Biradar, SL Nargund… - Advances in …, 2024 - Wiley Online Library
Tuberculosis, also known as TB, is a widespread bacterial infection that remains a
significant global health issue. This study focuses on conducting a thorough investigation …

Discovery of newer pyrazole derivatives with potential anti-tubercular activity via 3D-QSAR based pharmacophore modelling, virtual screening, molecular docking and …

P Modi, S Patel, M Chhabria - Molecular Diversity, 2023 - Springer
Tuberculosis is one of the leading causes of death of at least one million people annually.
The deadliest infectious disease has caused more than 120 million deaths in humans since …